Product

Shimadzu's GCMSsolution software sets a new standard for laboratory productivity in the 21st century by offering new and innovative solutions to the challenges of high-sample throughput, instrument control, diverse data handling, and integration with regulatory compliance. The latest version for the GCMS-QP2010 Series includes advanced functions like FASST, AART, and COAST for more powerful analysis.

New Functions

Toxicology Reporting Module
This newly-developed reporting module enables high-throughput drug testing laboratories to address specific productivity and QA/QC requirements. Corrective action plans established by most regulatory methods can be automated and samples may be evaluated during batch sequence injections for a variety of QA/QC parameters. In addition, laboratory productivity is enhanced by automating the data processing and reporting tasks associated with the daily workflow of drug screening analysis.

Download the flier here. (pdf - 584kb)

AART (Automatic Adjustment of Retention Time)
Retention times may change as a result of capillary columns being trimmed during maintenance or exchanged with a new one from a different lot. The re-validation process can be tedious, time-consuming, and expensive. With AART, this process is simplified, as this tool allows quick, easy, and accurate retention time correction, which enhances productivity and sample throughput by decreasing the time required for instrument method re-validation.

Download our AART whitepaper here. (pdf - 1.2mb)

FASST (Fast Automated Scan/SIM Technique)
The FASST technique opens up a new realm of FAST GC/MS as it enables the GCMS to acquire both Scan and SIM data on one peak. At a data acquisition frequency of 50 data points/second in Scan mode and up to 100 in SIM mode, high-quality results are achieved. Even with simultaneous data acquisition in both modes, there is no degradation of sensitivity.

COAST (Creation of Automatic SIM (Scan/SIM) Table)
COAST allows easy setup of SIM parameters using the SIM table automatic creation function, enabling appropriate parameters to be set automatically when using FASST. Easy setting of compounds and automatic creation of Scan/SIM parameters make high-sensitivity SIM chromatograms simple.

Features

One-Window Technology
"One-window" means that all data reduction information is now visible on one screen. Changing parameters for the viewed compound in the quantitation table simultaneously changes the display for the quantitative results, peak integration, spectrum, ion ratio, and peak locator on the TIC.

With "one-window" design, the user can simplify operation and put total control within the reach of the mouse. It's Simple and Easy!

Improved Method Development
Acquisition parameters for the GC oven, AFC flow and pressure profiles are displayed behind the TIC trace. Constant Linear Velocity optimizes separation with one-button operation. Tune the GC/MS by setting the software ion ratios, and GCMSsolution delivers every time. On the "acquire" display, a reference chromatogram behind the acquisition trace speeds method development. The ability to time-program the GC and MS is standard. High-speed GC/MS, high-pressure injection mode, Programmed Temperature Vaporization and Large-Volume Injection (PTV/LVI) are unique capabilities offered by GCMSsolution in conjunction with our AOC-20 autosampler.

Analytical Flexibility
With GCMSsolution, you can switch from scan to SIM 64 times within an analysis. Calibrate using 64 concentrations and up to 10 level repeats with 64 internal standards for maximum flexibility. Use any curve fit method that your work requires and set the fit type individually for each compound.

Simply Powerful Quantitation

Post-run processing places all needed information for quantitation visually available and graphically accessible. The Data Explorer keeps the working project visible and a simple "click and drag" loads the data file. Search for a file visually on the Preview window below the file or icon list.

The chromatogram window presents TIC, extracted ion profiles, SIM profile, Multiple Ion Chromatographs with integration, compound name labeling, and base peak m/z labels to easily identify the peaks.

The spectrum shown is generated from the integrated peaks or from manual spectrum generation and background subtraction. Right-mouse clicking provides library search results from any commercial library or up to 5 total libraries in any search.

The compound table holds the identification information for ion ratios or full spectrum scan data. By using scan spectrum, GCMSsolution provides more accurate compound identification and the "Compound Finder" can locate a compound anywhere in the chromatogram, ensuring easy method transfer between instruments and when changing columns.

Second Detector Option
GCMS-QP2010 adds a two-dimensional detector (FID or TCD) that makes GCMSsolution our most complete and flexible software package.

Wizards Work for You
Wizards lead you through creating methods, target compound tables, and batch acquire tables to simplify the process of using the system. Integration parameters, curve type, fit, and more are set using the wizard. Analyze all compounds using the same calibration type or each compound can have individual performance monitoring criteria. Wizards include:

• Compound Table Wizard  Leads you through the sequence of operations to build a compound table with minimal effort. Click for a sample image of this wizard.
• Batch Table Wizard  Creating new batch tables in GCMSsolution is simple. Each line of a batch can have visual basic programmability for pre-run, post-run or decision-based operations. Post-run or run-mode processing allows GCMSsolution to control and integrate many other lab systems functions into one automated process.
• Method Wizard  Set up parameters for analyzing samples using the GCMS-QP2010 automatically with the Method Wizard. Create simple or complex assays quickly and accurately. From the most experienced to new users, the wizard speeds your method development.

Quantitation Batch Viewer and Summary Printout
This advanced program allows multiple files to be simultaneously viewed and quantitatively reprocessed. Included are the capabilities to perform batch summary calculations for the entire batch as a run set, and to check calibration linearity while verifying the sample file data within the batch.

Multiple Point Background Subtraction
By taking background points before and after a qualitative peak, unknown samples are more easily identified.

Manual Spectrum Correction from the Mass Table with Library Search
When manual spectral correction is needed for column bleed or other known contaminants, they are removed from the mass table, allowing better library search results.

Mass Spectral Libraries
Various Libraries for your GCMS needs. Click here to find out more information.