Biomaterials

Shimadzu offers a complete range of instrumentation to support advancements in the field of biomaterials and new medical treatments, including regenerative tissue implants, orthopedics, drug delivery, and medical devices. Mechanical test equipment such as universal test machines and fatigue testers enable the evaluation of the biomechanical and physical properties of biological samples, tissue, biomaterials, elastomers, polymers, metals, and shape memory alloys. They can also be used to study the suitability and reliability of medical devices and packaging designs. Our advanced x-ray imaging systems can be used for the inspection of animal specimens and tissue used in experimental research, and our particle size analysis and life science instrumentation offer innovative solutions for the analysis of biological samples.

Featured Applications

Physical Property Testing Equipment for Biomaterials and Medical Applications

Physical Property Testing Equipment for Biomaterials and Medical Applications

To guarantee the safety and efficacy of medical equipment and technologies in the wake of medical breakthroughs, more active efforts are being made to reinforce the evaluation criteria and the regulations governing the standardization of measuring instruments and test methods. Medical equipment manufacturers and research organizations around the world are conducting research and development into medical equipment based on mechanical properties evaluation and finite-element analysis. Shimadzu Corporation is applying the technical expertise cultivated through physical testing, quality control, and full-scale testing in materials development to the fields of leading-edge medicine and biomaterials evaluation.


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Aggregation Analysis System for Biopharmaceuticals

Aggregation Analysis System for Biopharmaceuticals

The Aggregates Sizer aggregation analysis system enables the quantitative evaluation of particle amounts in the 0.1 μm to 10 μm range as a concentration (units: μg/mL or particles/mL). Aggregations of biopharmaceuticals can be categorized into 4 ranges: nanometer (<100 nm), submicrometer (100 nm to 1 μm), subvisible (1 to 100 μm), and visible (>100 μm), according to their particle size. Until now, particles in the submicrometer to subvisible portion of this range (100 nm to 10 μm) were generally measured by combining multiple methods.


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Observation of Organic Specimens with an X-Ray CT System and Creation of 3D Printed Molds

Observation of Organic Specimens with an X-Ray CT System and Creation of 3D Printed Molds

The inspeXio SMX-100CT system has a micro focus X-ray generator (max.100kV) and high sensitive image intensifier, making this system useful for the observation of soft materials (resin, bone etc.). The internal structures of small insects such as internal muscles and nerves can be observed nondestructively by CT imaging.

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Observation of a Mouse Femur Using an X-Ray CT System

Observation of Organic Things with X-Ray CT System and Molding created with 3D printer

At universities, pharmaceutical manufacturing companies and in other research fields, a variety of research using experimental animals is being conducted, including research into bone diseases, as well as drug administration evaluations, and fat measurements for metabolic research. The main experimental animals are rats, mice, and rabbits. In this context, X-ray CT systems are often used to observe and analyze the bones of small animals, and for research on the teeth of humans and small animals. Observations of small animals consists of in vivo CT imaging of living animals, and in vitro CT imaging of dead animals and excised parts. This article introduces imaging (in vitro) CT data from mouse femurs, taken using the inspeXio SMX-100CT, as well as analytical results from 3-dimensional analysis software utilizing the CT data.

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Journals & Papers

A biomechanical test model for evaluating osseous and osteochondral tissue adhesives

Philip Procter1,2*† , Michael Pujari-Palmer1† , Gry Hulsart-Billström1,3, David Wenner1 , Gerard Insley1,2, Sune Larsson3 and Håkan Engqvist1

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The Utility of 3D Digital Image Correlation for Characterizing High-Rate Deformation

annotti P. (2019) The Utility of 3D Digital Image Correlation for Characterizing High-Rate Deformation. In: Kimberley J., Lamberson L., Mates S. (eds) Dynamic Behavior of Materials, Volume 1. Conference Proceedings of the Society for Experimental Mechanics Series. Springer, Cham

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Industries

For Research Use Only. Not for use in diagnostic procedures.

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