Biomaterials and Prosthetic Testing
Testing, Analysis and Inspection of Biomaterials and Prosthetics
Shimadzu offers a complete range of instrumentation to support advancements in the field of biomaterials and new medical treatments, including regenerative tissue implants, orthopedics, drug delivery, and medical devices. Mechanical test equipment such as universal test machines and fatigue testers enable the evaluation of the biomechanical and physical properties of biological samples, tissue, biomaterials, elastomers, polymers, metals, and shape memory alloys. They can also be used to study the suitability and reliability of medical devices and packaging designs. Our advanced x-ray imaging systems can be used for the inspection of animal specimens and tissue used in experimental research, and our particle size analysis and life science instrumentation offer innovative solutions for the analysis of biological samples.
Physical Property Testing Equipment for Biomaterials and Medical Applications
To guarantee the safety and efficacy of medical equipment and technologies in the wake of medical breakthroughs, more active efforts are being made to reinforce the evaluation criteria and the regulations governing the standardization of measuring instruments and test methods. Medical equipment manufacturers and research organizations around the world are conducting research and development into medical equipment based on mechanical properties evaluation and finite-element analysis. Shimadzu Corporation is applying the technical expertise cultivated through physical testing, quality control, and full-scale testing in materials development to the fields of leading-edge medicine and biomaterials evaluation.
Aggregation Analysis System for Biopharmaceuticals
The Aggregates Sizer aggregation analysis system enables the quantitative evaluation of particle amounts in the 0.1 μm to 10 μm range as a concentration (units: μg/mL or particles/mL). Aggregations of biopharmaceuticals can be categorized into 4 ranges: nanometer (<100 nm), submicrometer (100 nm to 1 μm), subvisible (1 to 100 μm), and visible (>100 μm), according to their particle size. Until now, particles in the submicrometer to subvisible portion of this range (100 nm to 10 μm) were generally measured by combining multiple methods.
Observation of Organic Specimens with an X-Ray CT System and Creation of 3D Printed Molds
The inspeXio SMX-100CT system has a micro focus X-ray generator (max.100kV) and high sensitive image intensifier, making this system useful for the observation of soft materials (resin, bone etc.). The internal structures of small insects such as internal muscles and nerves can be observed nondestructively by CT imaging.
Observation of a Mouse Femur Using an X-Ray CT System
At universities, pharmaceutical manufacturing companies and in other research fields, a variety of research using experimental animals is being conducted, including research into bone diseases, as well as drug administration evaluations, and fat measurements for metabolic research. The main experimental animals are rats, mice, and rabbits. In this context, X-ray CT systems are often used to observe and analyze the bones of small animals, and for research on the teeth of humans and small animals. Observations of small animals consists of in vivo CT imaging of living animals, and in vitro CT imaging of dead animals and excised parts. This article introduces imaging (in vitro) CT data from mouse femurs, taken using the inspeXio SMX-100CT, as well as analytical results from 3-dimensional analysis software utilizing the CT data.
Journals & Papers
Does posterior configuration have similar strength as parallel configuration for treating comminuted distal humerus fractures? A cadaveric biomechanical study
Shih, CA., Kuan, FC., Hsu, KL. et al. Does posterior configuration have similar strength as parallel configuration for treating comminuted distal humerus fractures? A cadaveric biomechanical study. BMC Musculoskelet Disord 22, 440 (2021). https://doi.org/10.1186/s12891-021-04302-9
The Use of Silane Coupling Agents on Lithium Disilicate Glass Ceramic Repaired with Resin Composite
Klaisiri, Awiruth; Krajangta, Nantawan; Sriamporn, Tool; Phumpatrakom, Panupat; Thamrongananskul, Niyom.Journal of International Dental and Medical Research; Diyarbakir Vol. 14, Iss. 1, (2021): 169-172.
Conductive Biomass Films Containing Graphene Oxide and Cationic Cellulose Nanofibers for Electric-Heating Applications
Liang, S.; Wang, H.; Tao, X. Conductive Biomass Films Containing Graphene Oxide and Cationic Cellulose Nanofibers for Electric-Heating Applications. Nanomaterials 2021, 11, 1187. https://doi.org/10.3390/nano11051187
3D Printed Clamps for In Vitro Tensile Tests of Human Gracilis and the Superficial Third of Quadriceps Tendons
Grgić, I.; Wertheimer, V.; Karakašić, M.; Ivandić, Ž. 3D Printed Clamps for In Vitro Tensile Tests of Human Gracilis and the Superficial Third of Quadriceps Tendons. Appl. Sci. 2021, 11, 2563. https://doi.org/10.3390/app11062563
Flexural properties and dentin adhesion in recently developed self-adhesive bulk-fill materials
Philippe François1,2), Anis Remadi1), Stéphane Le Goff1), Sarah Abdel-Gawad1), Jean-Pierre Attal1,3), and Elisabeth Dursun1,4)
Use of Quickfix for tape fixation of chest tubes: a multi-center doctor-nurse questionnaire survey and fixing strength comparison study
Homma T, Ojima T, Shimada Y, Akemoto Y, Yoshimura N. Use of Quickfix for tape fixation of chest tubes: a multi-center doctor-nurse questionnaire survey and fixing strength comparison study. J Thorac Dis. 2020;12(3):493-503. doi:10.21037/jtd.2019.12.132
Transparent Nacre‐like Composites Toughened through Mineral Bridges
Advanced Functional Materials
Tommaso Magrini, Simon Moser, Madeleine Fellner, Alessandro Lauria, Florian Bouville, André R. Studart
A biomechanical test model for evaluating osseous and osteochondral tissue adhesives
Philip Procter1,2*† , Michael Pujari-Palmer1† , Gry Hulsart-Billström1,3, David Wenner1 , Gerard Insley1,2, Sune Larsson3 and Håkan Engqvist1
The Utility of 3D Digital Image Correlation for Characterizing High-Rate Deformation
annotti P. (2019) The Utility of 3D Digital Image Correlation for Characterizing High-Rate Deformation. In: Kimberley J., Lamberson L., Mates S. (eds) Dynamic Behavior of Materials, Volume 1. Conference Proceedings of the Society for Experimental Mechanics Series. Springer, Cham