A novel ion optical device to improve duty cycle of a Q-TOF mass spectrometer

Duty cycle of orthogonal Q-TOF mass spectrometer is limited by its mass range. The reason is that ions would disperse in space prior to enter the extraction region of TOF, due to ions’ velocity varying according to m/z. We proposed a new strategy to address the issue, by using a novel ion optical device “RF carpet trap”. Ions are firstly trapped in the device, and then being sequentially scanned out in a slow speed (~200Hz) by a reversed m/z order. A fast ion gate (~8kHz) followed can chop the ejected ion cloud and synchronize with the TOF pulser. Duty cycle of Q-TOF can be improved to be >50% in a wide mass range.

Content Type:
Poster
Document Number:
ASMS 2020 - TP 255
Product Type:
Liquid Chromatography Mass Spectrometry
Keywords:
LCMS-8040 Triple Quadrupole Liquid Chromatograph Mass Spectrometer (LC-MS/MS)
Language:
English
File Name:
TP255-ASMS-2020-Poster.pdf
File Size:
974kb

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