Analysis of Per- and Polyfluoroalkyl Substances (PFAS) Specified in EPA M533 Using the Triple Quadrupole LCMSMS

Recently, EPA announced a new method for testing short chain per- and polyfluoroalkyl substances (PFAS) in drinking water. Structures for select short chain and long chain PFAS2 are included in Figure 1. Method 5333 measures PFAS by isotope dilution anion exchange solid phase extraction and liquid chromatography/tandem mass spectrometry (LC-MS/MS). The lowest concentration minimum reporting levels (LCMRLs) for the method analytes range from 1.4 to 16 ng/L. Shimadzu Scientific Instruments was one of eight laboratories that participated in providing EPA with outside laboratory validation data along with a review of the method draft. This poster includes Shimadzu Scientific Instruments data from the validation study.

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Document Number:
ASMS 2020 - ThP 081
Product Type:
Liquid Chromatography Mass Spectrometry
Environmental, LCMS-8045 Triple Quadrupole Liquid Chromatograph Mass Spectrometer (LC-MS/MS)
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