Development of a Data Processing Approach to Support Ultra High-Throughput MS Acquisition

Ultra-High-throughput analytical systems (UHTS) are needed in various field of the industry to assay large quantities of samples in a short time or to improve response time. UHT-LC-MS systems have gained popularity thanks to the versatility of LC separation modes, high automation, sensitivity and selectivity of MS. In addition, other introduction modes such as Laser Diode Thermal Desorption are used for extremely short analysis. Hardware became extremely fast. However, still some time is needed for software to upload settings and receive the ready state between two samples. This extra amount of time can ruin the throughput of the system. A solution is to record all data in a single data file, but a software able to process it was needed.

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Document Number:
ASMS 2020 - ThP 578
Product Type:
Liquid Chromatography, Liquid Chromatography Mass Spectrometry
Nexera XR (40-Series) UHPLC System, LCMS-8050 Triple Quadrupole Liquid Chromatograph Mass Spectrometer (LC-MS/MS)
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