Evaluation of Automated Quantitative Analysis of the Doubly Charged Glycated β-Haemoglobin by MALDI-TOF MS

This approach opens a new world to time and cost-effective analysis of HbA1c within the clinical chemistry. Long-term control of the glycemic state of haemoglobin is the most important and reference tool for the management of diabetes. The Dutch diabetic association recommends monitoring the level of glycated haemoglobin (HbA1c) two to four times a year, depending on the type of diabetes. Several procedures and numerous commercial instruments, based mainly on chromatographic separation methods, are currently available for the determination of HbA1c in blood samples. In this study we have developed a method for automated quantification of HbA1c with MALDI-TOF.

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Document Number:
ASMS 2020 - TP 119
Product Type:
Life Science, MALDI-TOF Mass Spectrometry
Clinical Research, MALDI-8020 Benchtop Linear MALDI-TOF Mass Spectrometer
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