Ultrafast qualitative screening of mitragynine, MDMA, and THC in complex matrices by green technology direct probe ionization mass spectrometry

There has been substantial surge in the occurrence of illicit drug seizure worldwide. The seized drugs are found in various forms and matrices. This makes it inevitable for authorities to consider more advanced, versatile and rapid detection solutions. Mass spectrometry is the gold standard in forensic drug analysis and amongst the most discriminatory technique. However, extensive sample preparation is required for complicated matrices. Recently, development of Ambient ionization Mass Spectrometry (AMS), which allows samples to be investigated in open air and often with limited sample preparation, has been reported. Shimadzu’s AMS technology, Direct Probe Ionization Mass Spectrometry (DPiMS), was utilized to develop fast (1 min) and accurate screening for mitragynine, MDMA, and THC in complex matrices such as kratom drink, oil, and drug sachets.

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Document Number:
ASMS 2020 - TP 004
Product Type:
Liquid Chromatography Mass Spectrometry (LC-MS)
ASMS 2020, Forensics, Controlled Substances, LCMS-8060 Triple Quadrupole Liquid Chromatograph Mass Spectrometer (LC-MS/MS)
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