Webinars and Online Training - Industries

Webinars and Online Training

Cannabis and Hemp Testing Webinars

Learn more about our Cannabis and Hemp Testing Solutions

Detection of Typical GCMS Pesticides by APCI-LCMS in Cannabis

Presentation topics include: What is MS?, LCMS vs GCMS, Pesticide Analysis in Cannabis, LCMS Source Types, MRM Development and Optimization, Final Method Parameters, Sample Preparation, Matrix Effects, Representative Chromatograms, Calibration Curves, and LOQs

Detection of Typical GCMS Pesticides in Cannabis Webinar 

 

How to Increase Speed and Efficiency of Heavy Metals Testing in Cannabis

Join industry experts from Glass Expansion, CEM, and Shimadzu to learn about methods, optimization, and tips and tricks related to the analysis of heavy metals for the cannabis industry. This discussion will cover the complete analysis process, from digestion to data.

Heavy Metals Cannabis Webinar 

 

NIST Tools for Confidently Distinguishing Between Hemp and Marijuana

This webinar will focus on the analytical methods and procedures being developed at NIST for accurately measuring cannabinoids (THC, THCA, CBD, etc.) in Cannabis samples and the solutions provided by Shimadzu Scientific Instruments.

 

Tips and Tricks: Cannabis Sample Prep and Analysis by ICP-MS

Join us to learn a few tips and tricks to overcome common problems associated with the analysis of cannabis samples by ICP-MS.

ICPMS Tips and Tricks for Cannabis Webinar 

 
 

Clinical Research Webinars

Learn more about our Clinical Research Solutions

Brace Yourselves: The Shift to Mass Spectrometry for Clinical Analysis

There is a shifting trend in the analytical platform from immunoassay to mass spectrometry in clinical research and diagnostic lab in the past decade. This growing trend of mass spectrometry application in clinical lab is due to the superior selectivity and sensitivity of mass spectrometers. More importantly, mass spectrometry can analyse multiple compounds in a single analysis using much lesser sample amount compared to immunoassay. The application of mass spectrometry in various clinical analysis using Shimadzu’s Ultra Fast Mass Spectrometry (UFMS) Technology will be discussed in this webinar. Lastly, Shimadzu latest innovative technology in clinical automation and rapid screening will also be highlighted.

 

Direct Probe Ionization Mass Spectrometry (DPiMS) for High Throughput Analysis

Evolution of mass spectrometry (MS) hardware, especially ionization method, has drastically changed the landscape of MS applications. Direct Probe Ionization Mass Spectrometer (DPiMS) has the potential to pioneer new types of applications with the new ionization interface. The technique successfully incorporated the best of both worlds; high ionization efficiency of ESI and simplicity of MALDI. This was achieved by using an ultrafine needle to sample an extremely small volume of sample on its surface and subsequently applying high voltage to the needle to imitate an ESI probe. DPiMS is characterized by the microscopic sampling volume and high sensitivity for the amount sampled at a low ng/mL concentration range. For this, DPiMS can be a robust solution for the routine analysis of high-complexity matrices, such as plasma or food extract, as contamination of MS hardware can be perfectly mitigated. Moreover, direct sampling from solid samples causing minimal destruction might enable new applications such as real-time analysis of live tissues or cells.

DPiMS Webinar 

 

Energy & Chemicals Webinars

Learn more about our Energy and Chemicals Solutions

Analysis of Alcohols and Hand Sanitizers – Regulatory Compliance and Analytical Efficiency

In this webinar, our panel of experts will discuss the market for alcohol-based hand sanitizers, the current regulatory environment, as well as analytical solutions including gas chromatography, Fourier-transform infrared spectroscopy, and UV-Vis spectroscopy to ensure the purity, potency, and safety of alcohols and hand sanitizers.

 

Analysis of Sulfur Compounds in Hydrocarbon Matrices by ASTM D5504, D5623, and D7011 with a new GC-SCD

In this webinar, we will discuss the fundamentals of GC-SCD as well as common challenges, explore the unique design of Shimadzu’s new SCD and how it overcomes these challenges, and present data for this system’s applicability to ASTM D5504, D5623, D7011, as well as quantification of sulfur compounds in ethylene and propylene.

 

Analyzing Aromatics in Jet and Diesel Fuels Using LC-RID

Analysis of the chemical components of fuels is critical to ensuring their quality, combustion characteristics, and compliance with environmental regulations. This webinar will provide a background on the common industry test methods for fuels, the challenges associated with long-standing techniques, and explore Shimadzu’s HPLC-based solutions for the energy industry.

Analyzing Aromatics in Jet and Diesel Fuels Webinar 

 

Expanding Material Characterization Capabilities Using Pyrolysis GCMS

Have you ever wanted an alternate sample introduction method?  Maybe the sample of interest needs to be hotter than a standard inlet will reach.  Pyrolysis is a sample introduction technique that uses elevated temperatures to break down organic materials.  The starting samples can be anything from liquids to solids from many different application areas.  Attend to get your questions answered by the experts.

Material Characterization Capabilities Using Pyrolysis Webinar 

 

Reliable Sulfur Speciation by A Newly Designed GC SCD

This eLearning session introduces the operating principle of the SCD, as well as the innovations brought by Shimadzu to improve the productivity and minimize the instrument downtime. You will learn the various features of Shimadzu SCD which make it a reliable tool for analysing sulfur-containing compounds down to the trace level.

Sulfur Speciation Webinar 

 

RoHS : Regulatory compliance and it's solutions

Complying with the European Union (EU) or India's directive on Restriction of Hazardous Substances (RoHS) is an ongoing challenge for many companies. Too often, their compliance activities are unnecessarily complicated by a lack of understanding about what the regulation requires, and how to stay compliant when new restricted substances are introduced. Here in this webinar, our expert team will try to explain about the latest regulation, its implications, along with easy testing solutions to stay compliant to avoid any enforcement action.

RoHS Webinar 

 

Stay Safe! Comprehensive Analysis of Alcohols and Hand Sanitisers

In this webinar, our panel of experts will discuss the market for alcohol-based hand sanitizers, the current regulatory environment, as well as analytical solutions including gas chromatography, Fourier-transform infrared spectroscopy, and UV-Vis spectroscopy to ensure the purity, potency, and safety of alcohols and hand sanitizers.

 

Supelco’s Watercol™ Ionic Liquid Capillary Columns Coupled with TCD and Shimadzu’s BID for Detection and Quantitative Analysis of Water by Gas Chromatography

The determination of water content in alcoholic beverages, solvents and various consumer products such as foods, fuels, pharmaceuticals, and petroleum products is one of the most common types of chemical testing. Many techniques such as gravimetric analysis, gas chromatography (GC), Karl Fischer Titration, near infra-red spectroscopy, and others have been used for water quantification with good results. However, the limitations of these approaches can include high limits of detection, large sample sizes required for trace analysis, side reactions, the use of expensive consumables, and the production of chemical waste. Previous work by Prof. Daniel Armstrong and co-workers has described the use of ionic liquid GC capillary columns for the trace analysis of the water content in a wide variety of solvents. These columns were capable of providing a rapid and quantitative determination of water contents using very small sample amounts. This webinar further examines the characteristics of ionic liquid capillary columns for the GC analysis of water.

Analysis of Water by GC Webinar 

 

Environmental Webinars

Learn more about our Environmental Solutions

Emerging Water Quality Issues: Are You Ready to Monitor PFAS in your Water?

This webinar discusses the global trends and regulatory requirements pertaining to PFAS analyses (e.g. EPA 537.1) Several case studies on drinking water and environmental matrices are described to illustrate the difficulties and pitfalls of LC-MS/MS analyses and their solutions.

PFAS Webinar 

 

Monitoring and Quantitation of Nitrosamines in Water using GC-MS via Chemical Ionisation

Formation of nitrosamines, particularly NDMA, is prevalent in water treatment plants using chloramine as a disinfectant. NDMA is classified as a B2 carcinogen based on the induction of tumors at multiple sites in different mammal species exposed to NDMA by various routes. EPA 521 has been provided as the validated extraction and analytical procedure for monitoring of nitrosamines in drinking water. However, this method was developed using large volume injections (20 µL) and ion trap spectrometers in MS/MS chemical ionization (CI) mode (with methanol or acetonitrile). To avoid the complexity of large volume injections and CI, we present the alternative gas chromatography triple quadrupole electron ionisation method. Additionally, calibrants were prepared via an auto-sampler, from 1000 µg/ml commercially available standards.

Nitrosamines in Water Webinar 

 

Pyrolysis-GCMS: The Power of Mass Spectroscopy for Unveiling Plastic Contamination in the Environment

In this event, our two speakers will discuss the suitability of this technique for assessing the fate of microplastics in the environment. They will also present examples of how they have applied Py-GCMS for studying these contaminants in water, biosolids and seafood samples, among others.

Unveiling Plastic Contamination in the Environment Webinar 

 

RoHS : Regulatory compliance and it's solutions

Complying with the European Union (EU) or India's directive on Restriction of Hazardous Substances (RoHS) is an ongoing challenge for many companies. Too often, their compliance activities are unnecessarily complicated by a lack of understanding about what the regulation requires, and how to stay compliant when new restricted substances are introduced. Here in this webinar, our expert team will try to explain about the latest regulation, its implications, along with easy testing solutions to stay compliant to avoid any enforcement action.

RoHS Webinar 

 
 

Food & Beverage Analysis Webinars

Learn more about our Food and Beverages Solutions

Become a Digital Wine Connoisseur - Aroma Characterization using GCMS

Wine is a very delicate agricultural product, whereby, similar grape varieties can achieve very different aromatic profiles due to various cultivation conditions. With these variations, aroma profiling of wine is essential in the production process to identify consumers' preferences, formulating conditions and also quality control. These aromatic profiles are determined by a multitude of volatile compounds which are usually characterized comprehensively using GC/GCMS. In this webinar, Prof. Erich Leitner from Graz University of Technology will share on wine profiling and how GC/GCMS as analytical tool could help on different origin of different wines.

 

Food Contact Materials: GRAS* or Gross?

Food Contact Materials (FCM) are any materials that come in contact with food during processing, storage, preparation or serving. The safety of these FCMs must be evaluated as they can migrate into the food supply and contaminate the food with compounds like Per-and Polyfluorinated substances (PFAS), mineral oils (MOSH/MOAH), and leachables/extractables from plastics containers (bisphenol A, heavy metals). This webinar will provide an introduction to FCMs, discuss the challenges faced by the food industry, and present the latest analytical technologies for FCMs.

 

For the Love of Food! Food Safety and the Analysis of MCPD in Edible Oils

This webinar will clarify the regulatory status and analytical methods applied for the analysis of monochloropropane diol (MCPD) and glycidol contaminants in edible oils. Join us to learn how oil refining and food processing methods can be modified to minimise the in-situ generation of these contaminants in order to meet the regulatory requirements. While GCMS is the standard instrumentation to monitor the levels of these contaminants, multiple sample preparation steps must be adhered to in the various AOCS official methods. Find out how GERSTEL and Shimadzu come together to deliver the best automated solution for your food safety analysis needs. For the love of food!

 

LC-MS/MS methods for vitamin B and D analyses as per AOAC methods in infant and adult formulae

Vitamin B and D are important micronutrients to maintain good health. They are often fortified in various foods such as infant and adult formulae for added health benefits. Over the years, there are many AOAC methods dedicated to the analyses of different vitamin B and vitamin D compounds in infant and adult formulae. In recent years, many AOAC methods use LC-MS/MS to analyse both these vitamins. In this webinar, I will discuss about the different AOAC methods and the sample preparations in the analysis of vitamin B and D. I will also share some of the application development works done closely following AOAC methods using Shimadzu LC-MS/MS. 

 

Online Derivatization and UHPLC Analysis of Total Amino Acids in Animal Feed

This webinar gives you an introduction on fully automated pre-column derivatization of the amino acids and microwave digestion method which were adopted to further speed up and increase the analysis efficiency. A Shimadzu Nexera LC-40X3 with photodiode array (PDA) and fluorescence (RF) detectors were employed for the analysis. The Nexera LC-40X3 equipped with automated pre-treatment function allows several derivatization reagents to be aspirated sequentially from multiple vials and mixing within the needle and the sample loop. Microwave digestion procedure was employed to carry out both acid and alkaline hydrolysis in less than 30 minutes, which is much faster in comparison to the conventional hydrolysis up to 24 hours. Fluorescent (RF) detection was used for high sensitivity analysis (nM), while UV detection was compared, which shows its applicability for µM level quantitation of amino acids.

 

Shimadzu GC-MS/MS Solutions for Food Safety

This webinar provides a glimpse of the cutting-edge technology Shimadzu GCMSMS offers in the field of food safety. Agricultural industry faces a huge challenge of producing increasing quantities of food. While meeting such expanding global food demand, the safety and sustainability of food supply is of utmost importance. With the use of chemicals, significant reduction in crop losses and thus increased yield has been achieved. However, the resulting pesticide residues is of growing concern with its potential health risks. The exponential growth of chemical hazards and their regulations have brought several challenges to the food safety industry. It is particularly challenging for laboratories to accurately analyse large amounts of samples and detect the non-compliant ones. Understanding current laboratory requirements, GCMS-NX series along with its robust and sensitive hardware provides simplified user-friendly software for handling large multi-component data. Along with the unmatched hardware performance, Shimadzu also offers customizable databases and method packages as a total solution. 

 

Solutions for Halal Testing

In recent years, unauthorized blending of undeclared materials into food products has been a major concern among consumers. Such action violates customer rights based upon economical and safety values and it is also a critical problem for communities with ethical and religious belief. Both accidental and intentional adulteration of pork materials or alcohol into food and beverages are significant issue affecting Muslims as they have dietary restrictions on foods containing alcohol, pork and its-by-product, such as gelatin. With an estimated 1.6 billion Muslims worldwide, development of sensitive method for detection of porcine materials in food products is indispensable. In this webinar, we present Shimadzu complete solution for Halal testing.

 

Spice Up Your Life with MS: Workflows for High Throughput Pesticide Analysis by MS/MS in Challenging Matrices such as Spices and Tobacco

This exclusive Shimadzu Food Safety Webinar will provide an in-depth know-how about the various mass spectrometry (MS/MS) workflows that are needed to conduct high throughput pesticide analysis in challenging matrices. You will learn about the latest state-of-the-art technologies that mass spec leaders are using globally to deal with pesticide analysis in difficult matrices such as spices and tobacco. This webinar will be useful for anyone who is keen to learn about the latest advanced MS/MS technologies and will be particularly interesting for those who have faced difficulties while using challenging matrices.

 

Supporting Food Sustainability in Singapore

In this webinar, besides showcasing Shimadzu workflow solutions for food safety and production, we are honoured to have two distinguished guest speakers - Prof William Chen (Director, NTU Food Science & Technology Programme | Nanyang Technological University ) and Dr Toh Mingzhan (Research Fellow, Fermentation and Flavour Research Group, NUS) to discuss their contribution to the 30 x 30 initiative.

 

Taste Your Food, Not The Container: Off-Flavor Identification from Food Contact Material using Mass Spec

In celebration of our “50th anniversary of Mass Spectrometry”, we are pleased to introduce the Mass Discussion Series focusing of the innovative uses of Shimadzu's mass spectrometry instrument. For this edition, we are so glad to invite Prof. Erich Leitner from Graz University to share his work on off-flavour compound analysis. Off-flavors are not only give taints to food , but may also have an impact on human health. Generally, off-flavors are in trace amounts leaching from food packaging and/or food contact materials. In food safety market, determination of off-flavors and its concentration are essential in food production process, formulating conditions and also quality control. Join this Mass Discussion as Prof. Erich Leitner shares how his lab uses GC/GCMS to identify off-flavors from food contact materials. 

 

The Importance of Ultra Fast Mass Spectrometry for the Analysis of Chemical Hazards in Food & Beverages

Separation Science, in collaboration with Shimadzu,  offers an on-demand webinar and accompanying webinar companion that highlight the importance of ultra fast mass spectrometry for the analysis of chemical hazards in food and beverages. This is discussed in the context of the regulatory requirements for the analysis of contaminants in foods and a general overview of chemical hazards in foods.

 

Forensics Webinars

 

NIST Tools for Confidently Distinguishing Between Hemp and Marijuana

This webinar will focus on the analytical methods and procedures being developed at NIST for accurately measuring cannabinoids (THC, THCA, CBD, etc.) in Cannabis samples and the solutions provided by Shimadzu Scientific Instruments.

 

Thermal Desorption GCMS: Supporting Your Arson Analysis

Join us for our first Forensics Webinar! We will be covering the rapidly growing field of Arson as it pertains to TD-GCMS. Come and learn everything you need to know regarding Arson, and Fire Debris and how Shimadzu GCMS paired with thermal desorption will burn through the competition!

Thermal Desorption Webinar 

 

Using MRM/Product Ion Scan Mode in GC-MS/MS to Perform Detection and Differentiation of Synthetic Cannabinoids

Forensic chemists face the challenge of identifying new psychoactive substances (NPS), whereby the general structures of controlled drugs are modified to evade legislative banning. Hence, a plethora of synthetic cathinones and cannabinoids has been available to the public, causing a global social problem. It is therefore crucial that analytical methods are developed for identifying and differentiating new analogues of synthetic drug substances, to prevent potential trading and abuse. Additionally, drug legislation is made more challenging with the use of synthetic cannabinoid containing products, typically marketed as “herbal mixtures”, which consists of analogues of synthetic cannabinoids. In this study, simultaneous multi-reaction monitoring (MRM) and product ion scan (PIS) acquisition methods have been developed for detection and differentiation of isomeric synthetic cannabinoids.

Synthetic Cannabinoids Webinar 

 
 

Materials/Automotive Webinars

Common Standards for Mechanical Testing of Composites

​Fiber reinforced composites are increasingly being used in aerospace, automotive, and industrial applications to build lightweight, high-strength components and structures. Because of their high stiffness and anisotropic properties, a range of demanding tests are required to characterize their mechanical properties. This webinar will give a basic overview of the categories of mechanical testing for composite materials and provide some examples of common test methods and equipment requirements.

 

EPMA: A Revolutionary Approach to Micro-Analysis

Recently, there is an increased demand for surface observation & analysis of elemental distribution on sample surfaces, particularly for metals where it can be used for failure analyses. Being the most effective non-destructive technique for qualitative and quantitative elemental analysis, Shimadzu would like to introduce the Electron Probe Micro-Analyzer (EPMA) as a precise & accurate technique for surface characterization.

 

Expanding Material Characterization Capabilities Using Pyrolysis GCMS

Have you ever wanted an alternate sample introduction method?  Maybe the sample of interest needs to be hotter than a standard inlet will reach.  Pyrolysis is a sample introduction technique that uses elevated temperatures to break down organic materials.  The starting samples can be anything from liquids to solids from many different application areas.  Attend to get your questions answered by the experts.

Material Characterization Capabilities Using Pyrolysis Webinar 

 

Introduction to Light Emission Spectroscopy, with a focus on Fluorescence: Theory and Materials Characterization Applications

This webcast will consist of two parts. Part 1 will start off with a basic introduction to luminescence terminology and electronic theory. Particular attention will be given to photoluminescence, both fluorescence and phosphorescence. Part 2 will discuss several important materials characterization applications.

 

Latest Development in X-Ray Photoelectron Spectroscopy (XPS) Technology

Over the past few decades, the widespread utility and applicability of X-ray photoelectron spectroscopy (XPS) in research and development has made it the most popular and widely used technique of surface analysis. Our latest generation spectrometer, the AXIS Supra+, combines market leading spectroscopic and imaging capabilities with automation to ensure high sample throughput and ease of use. State-of-the-art performance including fast, high spatial resolution XPS imaging reveals the lateral distribution of surface chemistry and aids further characterisation with selected area analysis. We demonstrate the capabilities of the AXIS Supra+ and the technique of XPS in answering materials characterisation questions in application areas such as thin-films, biomaterials and Li-ion batteries.

 

Plastic Films, Fabrics, Nano Particles, and Butterfly Wings: Novel, “Outside the Box”, Uses For UV/Vis/NIR Integrating Spheres

This webcast will consist of two parts. Part 1 will start off with a basic introduction to UV/Vis/NIR integrating spheres. We will then consider samples, such as plastic films and colored Spectralon®, that illustrate how sphere diameter can impact spectral accuracy in both reflectance and scatter transmission measurements. Part 2 will discuss two novel integrating sphere applications within the rapidly growing technology field of nanomaterials.

UV-Vis Webinar 

 

RoHS : Regulatory compliance and it's solutions

Complying with the European Union (EU) or India's directive on Restriction of Hazardous Substances (RoHS) is an ongoing challenge for many companies. Too often, their compliance activities are unnecessarily complicated by a lack of understanding about what the regulation requires, and how to stay compliant when new restricted substances are introduced. Here in this webinar, our expert team will try to explain about the latest regulation, its implications, along with easy testing solutions to stay compliant to avoid any enforcement action.

RoHS Webinar 

 

UV/Vis/NIR Spectroscopy in the Arena of Materials Characterization Research and Quality Control: How Instrumental Performance and Accessories Define Success

Instrumental parameters that are crucial to measuring materials characterization samples are stray light, noise, resolution, and scan speed. In this presentation we will address how these inter-related parameters influence measurement success. It is vital that the proper accessory be employed to match the measurement desired. This presentation will address the function of integrating spheres and how they can be used to measure both diffuse reflection and transmission. Also discussed will be the difference between a relative and absolute reflection measurement. Finally, an overview will be given of important accessories related to the materials characterization marketplace.

UV-Vis Materials Characterization Webinar 

 

Pharmaceuticals & Biopharmaceuticals Webinars

Learn more about our Pharmaceutical & Biopharmaceutical Solutions

Analytical Technologies for COVID-19 Challenges

The COVID-19 pandemic has brought unprecedented challenges for the communities and economies worldwide, causing a profound effect on the lives of billions of people. While government and communities are trying to contain the spread, researchers are aggressively focusing their efforts towards finding a treatment and/or vaccine. Science is more important now than ever before. This webinar will feature the current analytical technologies and solutions that Shimadzu is committed to provide – such as analytical techniques for drug testing and vaccine research, production and testing of sanitizers and personal protective equipment and analysis of medical sewage waste.

 

Bioassay and Immunogenicity: A Perspective

Bioassay development is a complex process where analysts have to understand biological effect/mode of action of the drug in question and evaluate its immunogenicity. The method selected should be reliable, sensitive, and reproducible and should minimize errors due to biological variation and methodology. Join this session as Dr Dadke shares his expertise on bioassay development and describe the several potential candidates to evaluate immunogenicity of pharmaceutical drugs.

 

Bioprocess Challenges and Learnings

In Biopharmaceutical Manufacturing, the process is the product, and improving upstream processes alone is not enough, downstream damage control is crucial too. In this talk, Dr. Tiwari talks about the challenges in Bioprocess Manufacturing, which occur due to variabilities in the process. Variabilities can arise in the cell culture process as well as the purification process, and need to be monitored, assessed and controlled. Dr. Tiwari highlights the need and importance of in-process analysis of cell culture spent media by LC-MS/MS, with a case study on Cell Culture Profiling using Shimadzu LCMS-8060, which enables simultaneous monitoring of culture medium components. Based on the study on Cell Culture profiling, the media feed was optimized and a robust process control was established. This talk also covers the strategies which can be employed for robust manufacturing of a biosimilar, including process design for control of variability and the use of predictive modelling.

 

Characterization of Protein Aggregation in Therapeutic Peptides and Monoclonal Antibodies

Protein Aggregation, sometimes referred to as non-native aggregation, is one of the most challenging issues during biopharmaceutical product manufacturing, storage, shipping and administration. There has been increasing evidence of increased immunogenicity due to protein aggregation, hence it is essential to characterize and quantify aggregates in order to develop safe and stable biopharmaceutical products. In this talk, Dr. Jain discusses about the types, causes and mechanism of protein aggregation, and the need to characterize aggregates effectively. The various analytical techniques which can be utilized to characterize protein aggregates, and the basis of method selection, have also been highlighted, with an emphasis on Size-Exclusion Chromatography, Dynamic Light Scattering and Analytical Ultracentrifugation.

 

Development and Application of Alternative Ion-Pairing LC-MS/MS Method in Bioanalysis

Ion-Pairing Reversed-Phase Chromatography is a type of column chromatography in which ions in solution can be ‘paired’ or neutralised and separated as an ion pair on a reversed-phase column. Ion pairing reagents can greatly help with problematic chromatography, but any added ion pairing reagents into mobile phases also lead to signal suppression in LC-MS/MS analysis or diminished analytical column performance. In order to overcome these limits, an alternative ion-pairing LC-MS/MS bioanalysis method was successfully developed using Shimadzu LCMS-8060 in two projects. Not like the traditional ion- pairing LC-MS/MS analysis method, the ion pair reagent was not added to the mobile phase, but adding into the sample extract prior to LC-MS/MS analysis. This webinar will introduce 2 Application News for the quantitation of polymyxin B1, B2, B3 and Ile-B1 in human plasma and the bioanalysis of catecholamines including tyrosine, L-DOPA, dopamine and norepinephrine in cell culture samples.

 

Digital Transformation of Laboratory Workspace – Enhancing Workflow with Analytical Intelligence

As the world grapples with COVID-19 pandemic and plans for the aftermath, digitalization of laboratory workspace has become more urgent than ever before. In the future, most scientists will be telecommuting - away from the laboratory – for data analysis and reporting. Time spent in the laboratory itself will be solely for the purpose of analysing samples and pushing data into a secure database to be retrieved remotely. In this 45-min webinar, we will be discussing Shimadzu’s Informatics solutions – how different workflow solutions will facilitate the digitalization of your laboratory workspace by connectng your laboratory instruments, saving the data as well as allowing remote access and control for the users.

 

EDX: A Fast & Simple Technique for Pharmaceutical Elemental Analysis

AA or ICP-OES/MS is often viewed as the golden standard to analyze elements during the pharmaceutical manufacturing process, from drug discovery to the QA/QC of final formulations. While extremely accurate, these techniques have the downside of requiring the sample to be in liquid form when analyzing, resulting in a very arduous sample-preparation process and long analysis time. In this seminar, we would introduce Energy-Dispersive X-Ray Fluoroscopy (EDX) as an alternative technique to perform elemental analysis that requires little sample preparation, is easy to use and can provide results quickly; and how it could be used in various areas of the pharmaceutical industry.

 

EPMA: A Revolutionary Approach to Micro-Analysis

Recently, there is an increased demand for surface observation & analysis of elemental distribution on sample surfaces, particularly for metals where it can be used for failure analyses. Being the most effective non-destructive technique for qualitative and quantitative elemental analysis, Shimadzu would like to introduce the Electron Probe Micro-Analyzer (EPMA) as a precise & accurate technique for surface characterization.

 

Introduction to Extractables and Leachables Study

Recently there is an increasing demand for testing the pharmaceutical product to assess the quality of the packaging and storage materials. These can be a potential source for introduction of a variety of unwanted chemical compounds into the pharmaceutical products leading to health hazards in the patient. Extractable and Leachable study is a tool to screen, identify, and use the best quality packaging material so as to minimize the leaching of the unwanted chemicals into the pharmaceutical product. In this 33 minutes webinar, we will discuss the basic concepts of Extractable and leachable study and try to understand the preliminary workflow for the same. 

 

LCMS-9030 Q-TOF for peptide mapping and structural characterization of mAb biosimilars

Therapeutic monoclonal antibody (mAb) biosimilars are booming in Asia and across the world, as well as faces significant challenges in quality control. Peptide mapping plays a critical role in structure characterization of antibody drugs. This webinar will introduce 4 Application News for structure characterization of bevacizumab biosimilar using LCMS-9030 Q-TOF mass spectrometry, including peptide mapping, C-terminal sequencing, disulfide bond analysis, and N-glycan analysis.

 

New Nexera Series, the First AI Enabled and IoT Driven LC

As one of the most prominent innovators in LC technology, Shimadzu has set the New Benchmark in the LC innovation by developing the very first AI-enabled LC system, which allows Chemists to spend less time operating, and handling the instrument, as the instrument with its in-built Analytical Intelligence algorithm enables the system of performing automation workflow. The ultimate objective is to achieve minimized system downtime, optimize efficiency & maximize productivity, through the New Benchmarks in Intelligence, Efficiency and Design.

New Nexera Series, the First AI Enabled and IoT Driven LC Webinar 

 

Panel Discussion: Confidently Analyse Nitrosamine Impurities by GC-MS/MS & LC-MS/MS

Nitrosamine compounds are classified as probable human carcinogens by the International Agency for Research on Cancer (IARC). Ever since the first U.S. Food and Drug Administration (FDA) notification in June 2018 about levels of these impurities in pharmaceutical API, they have been a reason of continuous discussion globally for analytical scientist, patients and regulators. After June 2018, the number of recalls and 483’s have been on a rise for not only angiostenin II receptor blockers (-ARB, also called as sartans) but also for other products like Ranitidine, Metformin etc. FDA, European Medicine Agency (EMA) and International Council for Harmonisation (ICH) have constantly set and update the guidelines in measuring impurities in pharmaceutical products. Holistic solution to measurement of nitrosamines need both GC-MS/MS and LC-MS/MS technologies.

 

Pharma solutions by GC-MS/MS for Genotoxic Impurities

The following webinar talks about introduction to Genotoxic impurities, current regulations, Shimadzu solution with respect to method development workflow for GTI’s & well-developed applications for quantitation of GTI’s emphasising more on Nitrosamine quantitation in Valsartan & Metformin along with few other applications. It also discusses Shimadzu’s GCMS configurations and accessories as a complete solution for Pharmaceutical analysis. 

 

Streamline and Optimise your Analytical Workflow for Vaccine Testing

Vaccines are biological products used for the prevention or treatment of human diseases . They are made from immunogenic biological materials such as microorganisms, protein, polysaccharides and nucleic acids. Vaccines are produced using either traditional methods or modern biological technologies like genetic engineering. In the current COVID-19 pandemic situation, scientists and researchers around the world are not only trying to discover the COVID-19 cures, but also aiming to develop the vaccines to prevent the spread of the disease. In the webinar, we will share with you how Shimadzu analytical tools can help with the development and quality control of different types of vaccines products.

 

The Next Industry Standard GC: Nexis GC-2030

This webinar introduces Shimadzu's Next Industry Standard GC, Nexis GC-2030. The Shimadzu's premier gas chromatograph offers a modern approach to a classic chromatographic technique. Designed with the user in mind, new innovative features, exceptional performance and high-throughput capabilities will elevate your lab to the next level.

 

Toolkit for Treasure Hunt - Drug Discovery Made Easy

The hunt for novel drug candidate is a tedious and time-consuming process. A good workflow efficiency, from start of chemistry to purification to structural elucidation should streamline the discovery process and increase the success rate of developing novel candidate compound. In this Mass Discussion, Dr. Ramesh Appadurai from Syngene International and Pottayil G Sasikumar from Aurigene Discovery Technologies will share their experience in running successful R&D pipeline with the latest technology advancement. Let us also take a brief glimpse of Shimadzu's innovative drug discovery solutions which are designed to provide comprehensive and holistic workflow solution, ensuring faster result generation and maximizing ROI

 

Validation of Quantitative Method for Determination of Elemental Impurities in Pharmaceutical Products Following USP 232/233 on ICPMS-2030

24 targeted elemental impurities in three drug products were determined following new USP chapters <232>/<233> using Shimadzu ICPMS-2030. The method was evaluated and validated according to the procedures defined by USP <233> and combined with microwave digestion for sample preparation. Good calibration linearity, repeatability, stability and specificity were achieved for all 24 impurities. Low LODs and LOQs were obtained as compared to the target limits from USP <232>. The ICP-MS method applying universal He collision mode provides a high throughput method for routine elemental impurity analysis in pharmaceutical products.

 

For Research Use Only. Not for use in diagnostic procedures.

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