Nexera XR

Ultra High Performance Liquid Chromatograph

Nexera XR

The Shimadzu Nexera XR ultra high-performance liquid chromatograph (UHPLC) represents an increase in efficiency over the Prominence system, allowing customers to pursue high-speed, high-resolution chromatography.

The Nexera XR system provides accurate and reproducible results and has proven to be an indispensable tool for laboratories in a variety industries including pharmaceuticals, biochemistry, chemistry, environmental, and food science.


Capable of both HPLC and UHPLC Analysis

Ability for method transfer between standard HPLC and UHPLC (as low as 2 μm particle size columns) systems.

Flow Rates

Solvent Delivery Unit

Unrivaled solvent delivery units

World class pumps with improved performance at micro-flow rates and up to 5 mL/min.

Pulse-free solvent delivery that is essential for high quality data acquisition.

Accurate gradient programs can be achieved by low pressure gradient elution or a binary pump system. An optional quaternary solvent delivery valve can be used for gradient or isocratic elution


Increased Data Sensitivity and Reliability

The Nexera photodiode array detector (SPD-M30A) introduces a capillary type cell which gives higher sensitivity and lower dispersion for superior data.

The detector is temperature controlled to increase baseline stability and reproducibly.

Data Sensitivity


sample capacity

Needle-in-Flow Path Autosampler with Increased Throughput

Flow through the needle reduces sample carryover to an absolute minimum.

The high-performance measuring pump provides precision and accuracy for sample injections of even the smallest volumes (1 μL or less).

Increased sample capacity with full automation and high speed injections (minimum of 10 seconds).


LabSolutions Method Scouting for Method Development System

This system streamlines the process for more efficient and accurate method development by automatically switching between up to 96 combinations of unique separation conditions (with up to 6 columns, 8 mobile phases, and 10 gradient settings).

method scouting diagram

CBM web browsing software screen

CBM Web Browsing

Ability to monitor and control you LC system over a network

Temperature Control Graph

Large Capacity Column Oven with Precision Temperature Control

Oven temperature is calibrated at two different points to ensure a high degree of accuracy.

Large column compartment can comfortably hold up to three 300 mm columns, two flow control valves, two manual injectors, and a gradient mixer.

For Research Use Only. Not for use in diagnostic procedures.

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