Nexera XR

Ultra High Performance Liquid Chromatograph

Nexera XR

The Shimadzu Nexera XR ultra high-performance liquid chromatograph (UHPLC) represents an increase in efficiency over the Prominence system, allowing customers to pursue high-speed, high-resolution chromatography.

The Nexera XR system provides accurate and reproducible results and has proven to be an indispensable tool for laboratories in a variety industries including pharmaceuticals, biochemistry, chemistry, environmental, and food science.


Hardware Specifications (Limited)

Here are limited specifications for the typical components used in the Nexera XR system.

Detailed specifications are located within the component's pages.

System Controllers
Column Ovens


Degassing Unit
3 or 5 Lines (Volume 400 μL)
0.1 MPa (1.0 mL/min,10 MPa, Water)
Flow rate range
0.0001 to 5 mL/min
Flow rate precision
No more than 0.06% RSD or 0.02 min SD, whichever is greater
Gradient type
High-pressure / low-pressure mixing gradient
Gradient / concentration precision
±0.5% (specified conditions)
Maximum pressure 66 MPa (0.0001 to 3 mL/min)
44 MPa (3.0001 to 5 mL/min)


Injection method
Injection volume accuracy
±1% (at 50 μL injectiong, n = 10)
Injection volume range
0.1 to 50 μL (Option: 0.1 to 100 μL)
Injection volume reproducibility
RSD: 0.3% maximum (at 10 μL)
Samples capacity
Sample plate: 175 (1 mL), 105 (1.5 mL), 50 (4 mL), 2 (MTP/DWP plates)
Control plate: 10 (1.5 mL)
Sample cooler
Block cooling/heating, used together with defumidifying function
4 to 40°C
*No sampler cooler included in SIL-20AXR model


Oven Capacity
W220 × D95 × H365 mm
Temperature control range
Room temperature ± 10 to 85°C, Setting range 4 to 85°C

UV Detector

Wavelength Range
190 to 900 nm (with optional tungsten lamp)
Noise level
±2.5 × 10?6 AU, (250 nm, Specified condition)
Flow cell
12 μL (10 mm), 12 MPa
Option cell
High-Sensitivity: 8 μL (10 mm)
Semi-micro: 2.5 μL (5mm)

PDA Detector

Wavelength Range
190 to 800 nm
Noise level
±3 × 10?6 AU, (250 nm, Specified condition)
Flow cell
10 μL (10 mm), 8 MPa
Option cell
High-Sensitivity: 8 μL (10 mm)

For Research Use Only. Not for use in diagnostic procedures.

Top of This Page