Nexera UC - Supercritical Fluid Chromatography System - The Swiss Knif of Analytics

Nexera UC Analytical SFC System

Key Features

  • Unique BPR technology ensures accuracy and reproducibility
  • Low volume design for minimized peak dispersion
  • Direct, no-split connection to MS
  • Method scouting system with solvent blending for  automation of method screening
  • Flexible system configuration – LC/SFC switching possible
  • Online SFE sample preparation available
  • Unique GLS technology enables analytical fractionation system
  • Upgradeability of existing systems

Inspired versatility and reliability – the next era of SFC

User Benefits

  • Green technology that offers, faster separation, lower solvent consumption and reduced cost per sample
  • Complementary chromatographic selectivity to standard LC, especially beneficial for the separation of chiral compounds
  • Increased MS sensitivity can be achieved
  • Seamless method development workflow through dedicated, user-friendly software
  • Extensive column lineup for analytical and preparative scale

Supercritical fluid chromatography system

Supercritical fluid chromatography


  • SFC offers a supplementary chromatographic technique to conventional LC and GC analyses
  • Enables analysis of a wide range of non- to very polar analytes
  • Supercritical CO2 as mobile phase exhibits the solubility of a liquid with the diffusivity of a gas
  • SFC can be faster, more efficient, cheaper and more environmentally friendly than other methods
  • Application ranges from chiral screening to pesticide analysis, investigation of biomarkers or determination of polymer additives
Brochure PDF Icon


Nexera UC supercritical fluid chromatography system

Application PDF Icon


Supercritical Fluid  Chromatography and extraction – Application Handbook

Technical Report PDF Icon

Technical Report

Improving SFC Separation and Efficiency of Method Development

SFC Method Development

Preparative SFC

Analytical methods can easily be scaled up to semi-preparative SFC applications using the Nexera UC prep


A Virtual Lunch and Learn: Join us for a 3 Course Meal with a Tall Glass of Supercritical Fluid

For Research Use Only. Not for use in diagnostic procedures.

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