Impurity Analysis in Pharmaceutical Products with the Advanced Photodiode Array Detector SPD-M40

The following procedure is commonly used to measure the concentration of impurities in pharmaceutical products using area percentage normalization: prepare and analyze the standard solution at a concentration such that the height of the main peak will be within the linear range of the detector, then analyze multiple dilutions of the sample. Since the new photodiode array detector SPD-M40 has completely eliminated the effects of stray light during detection, it not only provides a wide dynamic range (linearity up to 2.5 AU as a specification value, typical value is more than 2.5 AU) but also achieves low noise and high sensitivity.

Content Type:
Application News
Document Number:
L538
Product Type:
High Performance Liquid Chromatography (HPLC & UHPLC)
Keywords:
HPLC, LC, nexera, spd-m40, pharmaceuticals, impurity,pda, Pharma & Biopharma, HPLC, LC, nexera, spd-m40
Language:
English
File Name:
HPLC_L538.pdf
File Size:
210kb

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For Research Use Only. Not for use in diagnostic procedures.

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