Prominence HPLC System

Prominence HPLC
The Shimadzu Prominence high-performance liquid chromatograph (HPLC) achieves an exceptional level of performance, reliability, and economy. Prominence HPLC covers a wide variety of flow rates and application goals.

Prominence is expandable to support a diverse range of applications:

  • Multiple solvent delivery options, a broad range of flows, and isocratic or gradient elution

  • Numerous detector options to cover a range of sample chemistries

  • Expandable valving options from simple to complex flow paths

  • Covering a broad range of analyses from analytical to semi-preparative, reversed phase, normal phase, Gel Permeation Chromatography (GPC) and Ion Chromatography (IC)

Click the name of a component to view more information. Prominence Components Degasser Pump Autosampler System Controller Detector Column Oven
CBM Web Browsing Software Screen
CBM Web Browsing

Ability to monitor and control you LC system over a network.

Solvent Delviery Unit
Unrivaled Analytical Solvent Delivery Units

World class pumps with unrivaled performance from semi-micro-flow rates (below 50 uL/min) up to semi-preparative flow rates (10 mL/min).

Pulse-free solvent delivery, essential for high quality data acquisition.

High accuracy gradient formation by low-pressure gradient elution or a binary high-pressure gradient elution.

Needle-in-Flow Path Autosampler with Increased Throughput

Flow through the needle reduces sample carryover to an absolute minimum.

The high-performance measuring pump provides precision and accuracy for sample injections of even the smallest volumes (1 µL or less).

Increased sample capacity with full automation and high speed injections.

Temperature Graph
Large Capacity Column Oven with Precision Temperature Control

Oven temperature is calibrated at two different points to ensure a high degree of accuracy.

Large column compartment can comfortably hold up to three 300 mm columns, two flow control valves, two manual injectors, and a gradient mixer.

Wavelength Comparison

Hardware Specifications (Limited)

Here are limited specifications for the typical components used in the Nexera XR system.

Detailed specifications are located within the component's pages.

System Controllers
Column Ovens
Degassing Unit 3 or 5 Lines (Volume 400 μL)
Pulsation 0.1 MPa (for water at 1.0 mL/min. and 7MPa) 0.3 MPa (for water at 1.0 mL/min. and 7MPa) 0.1 MPa (for water at 1.0 mL/min. and 7MPa)
Flow rate range 0.0001 to 10.0000 mL/min. 0.001 to 10.000 mL/min. 0.0001 to 10.0000 mL/min.
Flow rate precision No more than 0.06% RSD or 0.02 min SD, whichever is greater
Gradient type High-pressure / low-pressure mixing gradient High Pressure mixing
Gradient / concentration precision ±0.5% (specified conditions) 1.0% (specified conditions) ±0.5% (specified conditions)
Maximum pressure 40 MPa
Injection method Needle-in-flowpath
Injection volume accuracy ±1% (at 100 μL injection, n = 10)
Injection volume range 0.1 to 100 µL (Option: 0.1 to 50 µL, 1 to 500 µL, 1 to 2,000 µL)
Injection volume reproducibility RSD: 0.3% maximum (at 10 μL injection)
Samples capacity Sample plate: 175 (1 mL), 105 (1.5 mL), 50 (4 mL), 2 (MTP/DWP plates)
Control plate: 10 (1.5 mL)
Sample cooler Block cooling/heating, used together with defumidifying function
4 to 40°C
*No sampler cooler included in SIL-20AHT model
Oven Capacity W220 × D95 × H365 mm
Temperature control range Room temperature ± 10 to 85°C, Setting range 4 to 85°C
UV Detector
Wavelength Range 190 to 900 nm (with optional tungsten lamp)
Noise level ±2.5 × 10−6 AU, (250 nm, Specified condition)
Flow cell 12 μL (10 mm), 12 MPa
Option cell High-Sensitivity: 8 μL (10 mm)
Semi-micro: 2.5 μL (5mm)
PDA Detector
Wavelength Range 190 to 800 nm
Noise level ±6 × 10−6 AU, (250 nm, Specified condition)
Flow cell 10 μL (10 mm), 8 MPa
Option cell High-Sensitivity: 8 μL (10 mm)

Easy to use and intuitive data acquisition and analysis software to control your LC or GC systems

Several software packages to find the one that fits your needs; LabSolutions, LabSolutions CS, LabSolutions DB, etc.

Fully compliant with a variety of regulations and guidelines including:
  • CSV, Ministry of Health
  • Labor and Welfare ER/ES guidelines
  • FDA 21 CFR Part 11

LabSolutions Software Screen
Learn more >>
Shimadzu offers the following training classes:

HPLC-101: Shimadzu Modular HPLC Training with PM
HPLC-102: Shimadzu i-Series HPLC Training with PM

Click here to learn more!

Shimadzu has launched its interactive "Virtual Advisor" websites to further enhance customer service.

>> Learn about the Prominence Virtual Advisor.

For Research Use Only. Not for use in diagnostic procedures.