Nexera Preparative LC System

Preparative Purification Liquid Chromatograph

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Nexera Preparative LC System
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Flexible, easy-to-use preparative and purification liquid chromatography system

The Nexera Prep LC system is designed for fast and easy purification of target compounds

The Nexera Prep system helps you streamline the purification process. It automatically sets fractionation parameters, analyzes samples and removes salt from target compounds. These processes enable you to save time and focus on other tasks.

Shimadzu can offer preparative LC systems at all laboratory scales from analytical-prep to gram scale purification.

The system also features Open Solution™ – an open access software platform you can use to collaborate with other users and simplify complex workflows.

Key Features

Key features of the Nexera Preparative LC System
  • Automated purification process to save time
  • Versatile, customizable hardware configurations
  • Select the right pump, autosampler and detector for your needs
  • Flexible, durable design to support a range of applications
  • Expandable fraction collector for high-throughput applications
  • Small footprint to save space

Quick Specs

Pumps LC-20AP LC-20AR
Flow Rate 0.01 to 150.00 mL/min 0.01 to 20.00 mL/min
Maximum Pressure 42 Mpa 49 Mpa
Injector LH-40
Maximum Injection Volume Up to 2 mL, up to 20 mL (Optional available)
Cooling Function None
Compatible Containers and Quantities
10 mm O.D. test tube 540 pcs 1.5 mL vial 486 pcs
12 mm O.D. test tube 486 pcs 4.0 mL vial 252 pcs
13 mm O.D. test tube 360 pcs 13 mL vial 108 pcs
15 mm O.D. test tube 252 pcs 50 mL vial 54 pcs
17, 18 mm O.D. test tube 216 pcs 250 mL bottle 20 pcs
25 mm O.D. test tube 108 pcs 500, 1000 mL bottle 12 pcs
30, 35 mm O.D. test tube 54 pcs 96 well MTP/DWP 9 pcs
Fraction Collector LH-40 FRC-40
Maximum Flow Rate 150 mL/min
Cooling Function None
Compatible Containers and Quantities
10 mm O.D. test tube 540 pcs 4.0 mL vial 252 pcs
12 mm O.D. test tube 486 pcs 13 mL vial 108 pcs
13 mm O.D. test tube 360 pcs 50 mL vial 54 pcs
15 mm O.D. test tube 252 pcs 250 mL bottle 20 pcs
17, 18 mm O.D. test tube 216 pcs 500, 1000 mL bottle 12 pcs
25 mm O.D. test tube 108 pcs 96 well MTP/DWP 9 pcs
30, 35 mm O.D. test tube 54 pcs    
10 mm O.D. test tube 540 pcs 4.0 mL vial 252 pcs
12 mm O.D. test tube 486 pcs 13 mL vial 108 pcs
13 mm O.D. test tube 360 pcs 50 mL vial 54 pcs
15 mm O.D. test tube 252 pcs 250 mL bottle 20 pcs
17, 18 mm O.D. test tube 216 pcs 500, 1000 mL bottle 12 pcs
25 mm O.D. test tube 108 pcs 96 well MTP/DWP 9 pcs
30, 35 mm O.D. test tube 54 pcs    

 

Easy to use fraction collector and versatile liquid handler

  • FRC-40 Highly Flexible Fraction Collector

    The FRC-40 features an open-access design, a parameter simulation to ensure pure fractions, compatibility with many racks, and up to 4-channel acquisition. Up to 6 FRC-40’s can be configured on a single system for expanded fractionation needs.
     

    LH-40 Liquid Handler – Combination injector and fraction collector

    A combination of autosampler and fraction collector, the LH-40 liquid handler can perform everything from sample injection to sample recovery while suppressing contamination with a proprietary injection method.

  • Easy to use fraction collector and versatile liquid handler
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Use the MS signal to fractionate peaks and simplify prep work

  • Use the MS signal to fractionate peaks and simplify prep work

  • Fractions can be collected with confidence

    It can be difficult to prepare low UV absorptive components using just a UV signal as the trigger. However, using the MS signal as the trigger, preparative work can be performed simply. By specifying the m/z of the target component, fractions can be collected with confidence. The LCMS-2050 mass spectrometer enables high-sensitivity and high-resolution detection for preparative work with no target components omitted.

    Signals from various detectors can be used to trigger the fractionation. The optimal system configuration can be obtained for different samples and conditions.

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Nexera Prep System Selection Guide

  • Multiple configurations to meet specific user needs, from µg to gram scale, a variety of detection options, and the ability to collect 3000+ fractions*.


    *When using 6 fraction collectors with 10 mm OD tubing
  • Nexera Prep Selection Guide
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