LC/MS/MS Method Package for PFAS in Drinking Water

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Provides Methods for Analyzing Per- and Polyfluoroalkyl Substances in Drinking Water According to EPA Methods 533 and 537.1

LC/MS/MS Method Package for PFAS

The United States Environmental Protection Agency (US EPA) has standardized two methods for the analysis of Per- and Polyfluoroalkyl Substances (PFAS) in drinking water: EPA Method 537.1 and 533, encompassing a total of 29 PFAS. These methods were used as reference for creating a vetted LC/MS/MS Method Package for Analyzing PFAS in Drinking Water. This method package includes ready-to-use analytical conditions for EPA Methods 533 and 537.1, examples of analytical procedures for the methods, and various other information, such as precautions for sample preparation and analysis. Using this product, 52 PFAS compounds* in drinking water can be analyzed.

* Including internal standard substances, surrogates, etc.

 

Get your lab ready for analyzing PFAS by these methods with Shimadzu’s Method Package and the Guides that walk you through the different steps, from preparing your lab to analyzing your first samples.

Download Guide – EPA 537.1
Download Guide – EPA 533
Application News - EPA 537.1 for PFAS analysis with the Shimadzu LCMS-8050: Demonstration of instrument and method performance
Application News - EPA 533 for PFAS analysis with the Shimadzu’s LCMS-8050: Demonstration of instrument and method performance

LC/MS/MS Method Package for PFAS in Drinking Water

  • Ready-to-Use Analytical Methods
    The package includes optimized analytical conditions for LC/MS/MS analysis, enabling analysis to start as soon as the system, reagents, and columns are available. There is no need to conduct a time-consuming process to identify analytical conditions.
  • Illustrated Examples of Analysis Procedures
    Step-by-step diagrams guide the analysts, even the most unexperienced, through the steps of the EPA approved analytical workflows.
    In addition, each procedural step includes the corresponding text from the relevant EPA method as a reference when needed.
  • Precautions and Advice for Analysis
    Recommendations for ensuring an efficient analysis process are included.
Method Package PFAS - Analysis procedure

Optimized method satisfies QC acceptance criteria from EPA with shorter run times

 

original method vs method package - EPA 537.1

 

QC Requirements (EPA 537.1)

  • Peak shape? Pass!

    Peak Shape? Pass!

  • PFOS target and isomers

    Separation of isomers? Pass!

 

  • EPA method 577.1
  • EPA method 533

 

 

LabSolutions and LabSolutions Insight are trademarks of Shimadzu Corporation or its affiliated companies in Japan and/or other countries.

 

List of Targeted Compounds - EPA 537.1 / EPA 533

List of Target Compounds

 

>> Access more information about our solutions for the analysis of PFAS

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