LC/MS/MS Method Package for Restricted Chemicals in Textiles

For LabSolutions™ LCMS

Various restricted chemicals in textiles can be detected.

LC/MS/MS Method Package for Restricted Chemicals in Textiles

Public concern over the manufacturing process of textiles is increasing, especially in regard to the production of synthetic fibers. Manufacturers are beginning to adopt the OEKO-TEX® Standard 100, a globally recognized certification that ensures that textile products are free of harmful chemicals throughout the entire manufacturing process. In addition to currently regulated components, this method package provides analysis methods covering the major compounds in the OEKO-TEX®Standard 100 and voluntary regulations by various manufacturers.

  • Certain Aromatic Amines: 24 compounds

This analysis method contains MRM information on 24 compounds, including 2,4-xylidine and 2,6-xylidine in addition to 22 compounds targeted by regulations in the EU. It covers compounds targeted by regulations in a variety of countries including China and Japan.

 
  • Azo Dyes: 44 compounds

This targets compounds that are listed in the OEKO-TEX® Standard 100 and other regulations as carcinogenic dyes and allergic dyes. Additionally, it covers 27 compounds noted in EU Directive 2009/567/EC.

  • Perfluoro Compounds: 24 compounds

This analysis method targets PFOS and PFOA, which are included in the regulations, as well as their related salts, and even perfluoro compounds that are not included in the current regulations.

 

  • Alkylphenol Ethoxylate (APEO): 2 compounds Alkylphenol (AP): 4 compounds
 This covers 2 compounds—nonylphenol ethoxylate and octylphenol ethoxylate, listed in ISO18254, and the 4 main alkylphenols.
 
 

MRM Chromatogram for Azo Dyes

Shared Analytical Columns

This method package contains 6 separate analytical methods. A shared column is used for the 5 analyses, excluding the certain aromatic amines. Switching between the analytical methods can be done seamlessly by using a LPGE valve and built-in column switching. This is shown in the figure below.

Example of a System Configuration Using Column Switching

LC/MS/MS Method Package for Restricted Chemicals in Textiles

Overview of the Methods Contained in This Method Package

  Method 1 Method 2 Method  3 Method  4 Method  5 Method  6
Target
Compounds
24 certain
aromatic amines
44 azo dyes 7 azo dyes 24 perfluoro
compounds
2 APEOs 4 APs
Column Shim-pack FC-ODS
(2.1 mmID x 150 mm, 3 µm)
Shim-pack FC-ODS
(2.1 mmID x 75 mm, 3 µm)
Shim-pack FC-ODS
(2.1 mmID x 75 mm, 3 µm)
Shim-pack FC-ODS
(2.1 mmID x 75 mm, 3 µm)
Shim-pack FC-ODS
(2.1 mmID x 75 mm, 3 µm)
Shim-pack FC-ODS
(2.1 mmID x 75 mm, 3 µm)
Mobile Phase A 5 mmol/L
ammonium
acetate-water
5 mmol/L
ammonium
acetate-water
5 mmol/L
ammonium
bicarbonate-water
5 mmol/L
ammonium
acetate-water
10 mmol/L
ammonium
acetate-water
Water
Mobile Phase B Acetonitrile
5 mmol/L ammonium
acetate-acetonitrile:
( 9 : 1)
Acetonitrile Acetonitrile Acetonitrile Acetonitrile
Run Time 13 min 20 min 10 min 13 min 7 min 11 min

Precautions
LabSolutions LCMS Ver. 5.93 or later is required.

LabSolutions and Shim-pack are trademarks of Shimadzu Corporation.
The OEKO-TEX® label is an internationally registered trademark legally protected by the Madrid Agreement.

For Research Use Only. Not for use in diagnostic procedures.

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