HPLC/UHPLC Method Scouting System - Features

Maximizing Efficiency for Method Development

Flexible System Options

Method scouting can now be performed with Shimadzu's diverse LC product line-up. Choose the system suited to your laboratory environment, whether for SFC investigations or simple investigations on compact systems.

Nexera TM Method Scouting System

 

  • Investigate analytical conditions with automated switching of columns and mobile phases
  • Compatible with systems including 130 MPa UHPLC models or UHPLC-like models with method transfer

 

Nexera method scouting

 

Supercritical Fluid Chromatograph Nexera/UCs UHPLC/SFC Switching System

 

  • Optimized for method investigation of chiral compounds
  • Also compatible with LC/SFC switching, and can investigate various separation modes

 

Supercritical Fluid Chromatograph Nexera/UC/UHPLC/SFC

 

i-Series Method Scouting

 

  • Saves costs in transferring to routine testing
  • Space-saving, low-cost design

 

i-Series Method Scouting

 

Fully Automated Method Scouting

Combine Method Scouting System with Method Scouting Solution dedicated software to achieve substantial efficiency improvements across all operations from method creation to data acquisition and analysis.

Fully automated method scouting

Leave Your Method and Analysis Scheduling to Method Scouting System

Usually when method scouting, a method has to be created every time the column or mobile phase is switched. For example, 100 combinations of analytical conditions leads to 100 method files, not only creating a huge amount of labor but also increasing the risk of operational mistakes. Method Scouting System is intuitive to operate and can automate these changes in analytical conditions, allowing you to use your resources more efficiently.

Leave your method scouting and analysis scheduling to method scouting system

 

Labor-Saving Mobile Phase Blending

The mobile phase blending function in Method Scouting System allows you to quickly adjust the salt concentration, pH, and organic solvent ratio on-line using only a few pre-prepared solvents, and quickly search for suitable conditions. This significantly reduces the time required to prepare and evaluate mobile phases. The integrated i-Series LC system can also perform different types of mobile phase blending, two for water-based and two for organic solvents, using a low-pressure gradient.

labor-saving mobile phase blending

 

Improved Operating Rates with Automation of Analysis Sequences

Purge conditions and equilibration during automatic switching of mobile phases and columns are key issues in method scouting. With Method Scouting Solution, these and all laboratory operations can be performed automatically based on conditions set in advance, from automated control to system checks and system shutdown.

labor-saving mobile phase blending

 

Seamless Evaluation of Results in a Multi-Data Report

The mobile phase blending function in Method Scouting System allows you to quickly adjust the salt concentration, pH, and organic solvent ratio on-line using only a few pre-prepared solvents, and quickly search for suitable conditions. This significantly reduces the time required to prepare and evaluate mobile phases. The integrated i-Series LC system can also perform different types of mobile phase blending, two for water-based and two for organic solvents, using a low-pressure gradient.

labor-saving mobile phase blending

Optimization and Robustness Evaluation

Simple to Set Conditions for Optimization

After choosing the columns and mobile phases, gradient conditions need to be optimized. Using Method Scouting Solution, it is simple to create an analysis schedule which changes these conditions automatically.

Simple to setup conditions for optimization

 

Efficient Robustness Evaluations

Method Scouting Solution can import any experimental design (Excel® format) and execute the analysis schedule. It can finely adjust analytical parameters such as flow rate and oven temperature to streamline robustness assessments that require multiple runs.

Efficient Robustness Evaluations<

 

Improve Efficiency Even With Standard LCs

Operational efficiency can be improved even with a standard hardware configuration in the optimization and robustness evaluation stages that do not require automatic switching of mobile phases and columns. Method Scouting Solution is compatible with LCs that do not include mobile phase or column switching valves, so you can use your current LC for more efficient method development.

Improve Efficiency even with standard LCs

Interface for a simple configuration

Seamless Method Migration with LabSolutions™ CS

Once the optimal conditions are determined, they may be applied as general-purpose analysis conditions and transferred to other working departments. The data needs to be managed over long time periods and retrieved smoothly when needed. The combination of LabSolutions CS and Method Scouting Solution not only makes the method development process more efficient, but also streamlines a series of workflow tasks from reporting results to other departments to transferring methods.

Seamless Method Migration with LabSolutions

 

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