Two PFAS compounds, PFOA and PFOS have been named as hazardous substances under CERCLA allowing EPA to enforce monitoring and cleanup of contaminated sites. EPA has proposed including these and additional PFAS to RCRA regulations. The most used technique for PFAS analysis are Tandem Liquid Chromatography Mass Spectrometry or LC-MS/MS. Other approaches, such as single quadrupole LCMS, High Resolution LCMS, or GCMS may be used depending on the objectives of the analysis.
Adsorbable Organic Fluorine (AOF) is a screening method designed to detect additional PFAS compounds not captured by chromatographic methods. Fluorinated pesticides and pharmaceuticals may also be detected.
Shimadzu offers a variety of analytical solutions for PFAS testing in environmental samples in accordance with the following standardized methods.
EPA Method 1633, Revision A, Analysis of Per- and Polyfluoroalkyl Substances (PFAS) in Aqueous, Solid, Biosolids, and Tissue Samples by LC-MS/MS
ASTM D8421 Standard Test Method for Determination of Per- and Polyfluoroalkyl Substances (PFAS) in Aqueous Matrices by Co-solvation followed by Liquid Chromatography Tandem Mass Spectrometry (LC/MS/MS).
SW-846 Method 8327 Per-and Polyfluoroalkyl Substances by Liquid Chromatography/Tandem Mass Spectrometry