A simple dilute-and-shoot LCMS method for the determination of free and modified amino acids in dietary supplements

We present here the direct determination of free and modified amino acids typically found in commercially available dietary supplement formulations such as tablets, capsules, and powders using liquid chromatography-mass spectrometry (LCMS). Dietary protein is composed of 20 different amino acids. The consumption of amino acids individually has been proposed to enhance performance and prevent mental fatigue. Amino acids are among the top five most popular sports supplements. Different formulation types are currently available in the market such as tablets, capsules, and powders. We report here a LCMS method that can analyze all 20 L-amino acids and modified amino acids in a single analytical run in various formulations of dietary supplements.

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Document Number:
ASMS 2020 - ThP 100
Product Type:
Liquid Chromatography Mass Spectrometry
Food, Beverages, LCMS-2020 Single Quadrupole Liquid Chromatograph Mass Spectrometer (LC/MS)
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