Monochloropropanediols (MCPDs) are unintentionally produced from edible oils and
infant formula. MCPDs are generated from digesting vegetable protein with hydrochloric
acid and be formed by heating process. It has been reported long term intake of MCPDs
affects negative impacts to the kidney and androgenesis.
MCPDs fatty acid esters, glycidol fatty acid esters are also monitored in purified edible
oils. In animal experiments, most of MCPDs fatty acid esters and glycidol fatty acid esters
are decomposed in the intestinal tract and absorbed as MCPDs. EFSA investigated and
evaluated the intake of MCPDs, MCPDs fatty acid esters and glycidol fatty acid esters.
EFSA concluded it needs to be researched in detail, but efforts to reduce them are
We reported GCMS quantification method of 3-MCPD, 3-MCPD fatty acid esters and
glycidol fatty acid esters.