Direct Analysis of Glyphosate, Glufosinate and AMPA in Foods Using a Triple Quadrupole LC/MS/MS

Glyphosate and glufosinate are non-selective herbicides used for various purposes in both the agricultural and domestic sectors. For grains, in particular, they are used as pre-harvest herbicides to reduce the work needed for harvesting, and the maximum residue limits (MRLs) has been established by country or regions. MRLs of glyphosate adopted by the Codex Alimentarius, EU, US and Japanese authorities are shown in Table 1 (as of October 2019). When degraded in soil and water, glyphosate produces AMPA as a metabolite. Since glyphosate, glufosinate and AMPA are all highly polar compounds, it is difficult to optimize retention in the reversed phase mode of HPLC. Therefore, analysis usually employs derivatization with active regent such as FMOC. In this study, we examined a method that allows direct analysis in food products, such as grains and fruits, pretreated by the QuPPe method and good recovery and reproducibilities in order to utilize for all food product analysis.

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Document Number:
ASMS 2020 - ThP 104
Product Type:
Liquid Chromatography Mass Spectrometry
Food, Beverages, LCMS-8060 Triple Quadrupole Liquid Chromatograph Mass Spectrometer (LC-MS/MS)
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