Tutorial: Fundamentals of GC-MS
Sample molecules are ionized in the ion source after chromatographic separation by a GC. The structure and function of the ion source will be explained here.
A quadrupole(QP) mass analyzer is most extensively used for GC-MS analysis. The mechanical structure of a QP mass analyzer and its principles will be explained.
Scan Mode and SIM Mode
Scan Mode and SIM Mode are the generally used analysis mode. Operation principles of the two modes will be explained, and a new analysis mode will be introduced.
An electron multiplier is generally used as a detector on a mass spectrometer. The structure of an electron multiplier system will be described here.
The mass spectrometer is housed in a vacuum. The basic knowledge of vacuum system, which is needed to understand GC-MS analysis, will be provided here.