LC/MS/MS PFAS Database
For LabSolutions LCMS

Perfluoro and polyfluoroalkyl substances (PFASs) are widely used for their water-repellent and heat-resistant properties, but their persistence, bioaccumulation, and toxicity are also seen as problematic. PFAS regulation varies worldwide, with some countries restricting certain PFAS compounds, while others are expanding monitoring, reporting, and drinking water standards. This product includes MRM conditions for 124 PFAS components, together with ready-to-use analytical methods corresponding to eight official methods.
It also provides a comprehensive solution for developing new PFAS analytical methods by combining the extensive database with LabSolutions Connect MRM.
Includes Ready-to-Use Analytical Methods Compliant with Eight Official Methods
This product includes optimized LC/MS/MS analysis method files for the following official methods: EPA 533, EPA 537.1, EPA 1633A, ISO 21675:2019, DB32/T 4004-2021, ASTM D7968-23, ASTM D7979-20, and ASTM D8421-22. Analysis can begin immediately using the prescribed column and conditions, eliminating the method development and optimization typically required for HPLC separations.
Chromatogram Examples

Includes MRM Conditions for 124 Perfluoro and Polyfluoroalkyl Substances (PFASs)
The LC/MS/MS PFAS database contains optimized MRM transitions and acquisition parameters for PFAS analysis across environmental, food, and related matrices. The database contains MRM acquisition parameters for 80 target analytes and 44 internal standards, including optimized transitions and collision voltages.

Supports Method Development Using LabSolutions Connect MRM
The analyte acquisition parameters included in this product can be managed using LabSolutions Connect MRM (optional). By importing a text file containing target analyte information, LabSolutions Connect MRM automatically retrieves the required data from the database, enabling easy creation of new analytical methods. This product includes both a database file (.db) and a searchable text file (.csv). The database can be customized to meet specific analytical needs, making it suitable for PFAS analysis across a wide range of application fields.

System Requirements
- LabSolutions LCMS Ver. 5.135 SP1 or later.
- LabSolutions Connect MRM Ver. 3.2 or later.
News / Events
-
ASMS (American Society for Mass Spectrometry) 2026
May 31 - June 4
San Diego Convention Center
San Diego, CA
Suite 5, 6 -
Shimadzu Scientific Instruments Inc. Opens New Laboratory in the San Francisco Bay Area -Accelerating New Product and Business Development for the Pharmaceutical and Life Science Fields
Shimadzu Corporation has positioned North America as a strategic focus area and is committed to expanding its business. Through this South San Francisco Lab, the company aims to position itself as a market leader by delivering unique, next-generation solutions that contribute to the advancement of the industry.
-
Shimadzu Announces New LCMS-8065XE Triple Quadrupole Mass Spectrometer
Shimadzu Scientific Instruments announces the LCMS-8065XE, the latest evolution in triple quadrupole mass spectrometry that redefines analytical excellence with world-class sensitivity, efficiency and sustainability.
-
Shimadzu Announces New LCMS RX Triple Quadrupole Mass Spectrometry Series
Shimadzu Scientific Instruments announces the new LCMS RX series of triple quadrupole mass spectrometry instruments. These advanced systems are supported by integrated hardware and software technologies to ensure reliable and robust results at lower operating costs, even under the most challenging and dynamic laboratory environments.
-
Innovative Technology Developed by Shimadzu and Washington University is Expected to Improve Healthy Life Expectancy
-
New Q-TOF LCMS-9050 Delivers Exceptional Mass Accuracy and Fast, Stable Polarity Switching