Fraction Collectors

FRC-40 Fraction Collector for High-Performance Liquid Chromatography HPLC

FRC-40 Fraction Collector

The FRC-40 for high-performance liquid chromatography (HPLC) significantly advances preparative scale fractionation by simplifying purification procedures, offering an improved purification workflow, and providing more efficient use of bench space.



  • Parameter Simulation ensures pure fractions.
  • Parameters can be changed during acquisition to maximize efficiency.
  • Up to 4-channel acquisition ensures that multiple detectors can be used simultaneously.

Select Peaks to be Collected, Obtain Fractionation Parameters Automatically

Easy to Use

  • Compatible with many racks corresponding to the intended fraction volume.
  • Open access design allows a single system to be shared by multiple users
  • Innovative sample rescue function minimizes sample loss when errors occur.

Space-Saving Design

  • Up to six fraction collectors can be connected simultaneously.
  • Can accommodate up to 3,240 fractions (6 FRC-40's, 10 mm tubes).
  Maximum Capacity
(1 x FRC-40) / (6 x FRC-40)
10mm test tubes 540 / 3,240
18mm test tubes 216 / 1,296
25mm test tubes 108 / 648
35mm test tubes 54 / 324
250 mL bottles 20 / 120
500/1,000 mL bottles 12 / 72
96-well MTP or DWP 9 [864] / 54 plates [5184 wells]
FRC-10A Fraction Collector

FRC-10A + CBM-20A

FRC-10A Fraction Collector

A proprietary band function enables obtaining accurate fractions even when the peak elution time varies, by catching the target component according to variations in the chromatogram. If connected to workstation software, fractions can be simulated on screen to determine whether or not the fraction program is appropriate.


Small and Large Volume Collection Capacity

The FRC-10A collects both analytical and preparative fractions. The standard configuration has a 144 5mL vial capacity. The large volume kit can be added for large volume collection.

Precise Peltier Temperature Control

For automated collection of thermally-labile fractions, Peltier temperature control keeps temperatures stable within a 4-70º C range.

Simplified Graphical Parameter Entry

Set up fractionation parameters graphically from the SCL-10AVP System Controller. Eliminate the guesswork of determining slope and level values.

Fraction Collection Flexibility

Tailor the collection to your application requirements.Choose from collection criteria such as volume, threshold, and peak purity. A precise peak division feature ensures high purity fractions. The FRC-10A automatically adjusts for retention time shifts, so that only the peak of interest is collected. Our slope-override capability enables continued collection, even when the detector signal is off-scale.

Drive System and Fraction Collection Methods Arm-Movement X-Y System
Select either solenoid valve or direct through nozzle
Fraction Modes Manual or programmed fraction collection by combining 14 types of parameters, such as slope, level, and band
Number of Fractions 16 to 144
Collection Tubes Glass: 3.5, 5, 20, 32, or 50 mL, or user supplied
Polypropylene: 4.5, 5, 25, or 50 mL, or user supplied

A CBM-20A or SCL-10AVP controller is required to control FRC-10A fraction collectors.

For Research Use Only. Not for use in diagnostic procedures.

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