High Performance Liquid Chromatography (HPLC & UHPLC)

HPLC has, without a doubt, grown to be the most popular and versatile of all analytical techniques in laboratories today. HPLC can be used for applications in such diverse industries as food and beverages, forensics, pharmaceuticals, drug discovery, environmental, and petrochemical. HPLC features a wide range of modules and components, including data systems, with an outstanding lifetime, high precision, and practicaly maintenance-free operation. Shimadzu has the resources to meet user requirements in nearly every market and application.
Analytical HPLC/UHPLC Systems

Nexera X3 (40-Series) UHPLC System
Nexera X3 excels in high throughput environments requiring fast separations. The system easily handles small ID UHPLC columns with sub-2 micron particles for high efficiency chromatography. Five minute run times are the norm.

Nexera XS (40-Series) UHPLC System
Nexera XS excels at fast separations, easily handling small ID UHPLC columns with sub-2 micron particles or the popular SPP phases for high efficiency and lower back pressure. A common XS configuration may have a 4-channel solvent selection valve on each pump providing versatility for method development. Five to ten minute run times are the norm.

Nexera XR (40-Series) UHPLC System
Nexera XR is perfect for fast separations using the popular SPP column phases for high efficiency and lower back pressure. This system offers a rugged and forgiving UHPLC workflow. Five to ten minute separations are the norm.

LC-40 HPLC System
Our LC-40 system is the workhorse for everyday HPLC, whether using traditional 5 micron fully porous LC columns or the popular SPP column phases for high efficiency separations with lower back pressures. Ten to 20 minute run times are the norm.

i-Series Integrated HPLC and UHPLC Systems
Redefining integrated LC technology by adding innovative, intelligent and intuitive features to existing performance excellence, the new integrated i-Series HPLC/UHPLC delivers outstanding data quality, improved workflow efficiency, and maximum uptime.
Preparative HPLC/SFC Systems

Nexera Prep HPLC
Rugged and reliable HPLC purification of compounds

Nexera Prep SFC
Rugged and reliable SFC purification of compounds
HPLC Application Specific Systems

Application Specific Analyzers based on the i-Series Plus
Application specific systems for the analysis of cannabis, hemp, bioethanol, and more

Nexera UC (SFC/SFE) System
Supercritical fluid extraction and chromatography (SFC/SFE) in a single system

Gel Permeation Chromatography Systems
Analytical systems optimized for GPC/SEC

Prominence Ion Chromatograph
New Shimadzu Ion Chromatograph
Analytical HPLC/UHPLC Components
HPLC Solution System Packages

Nexera-i MT Method Transfer System
Providing easy, seamless method migration in one instrument

HPLC/UHPLC Method Scouting System
Automatic column, eluent scouting in analytical methods development