High Performance Liquid Chromatography (HPLC & UHPLC)

HPLC has, without a doubt, grown to be the most popular and versatile of all analytical techniques in laboratories today. HPLC can be used for applications in such diverse industries as food and beverages, forensics, pharmaceuticals, drug discovery, environmental, and petrochemical. With a wide range of systems and components, including data systems, and outstanding reputation for long life, precision, and practically maintenance-free operation, Shimadzu has the resources to meet user requirements in nearly every market and application.

Nexera UHPLC - learn more

HPLC Knowledge Base - Learn More

Analytical HPLC/UHPLC Systems

Nexera X3 (40-Series) UHPLC System

Nexera X3 (40-Series) UHPLC System

Nexera X3 excels in high throughput environments requiring fast separations. The system easily handles small ID UHPLC columns with sub-2 micron particles for high efficiency chromatography. Five minute run times are the norm.
Nexera XS (40-Series) UHPLC System

Nexera XS (40-Series) UHPLC System

Nexera XS excels at fast separations, easily handling small ID UHPLC columns with sub-2 micron particles or the popular SPP phases for high efficiency and lower back pressure. A common XS configuration may have a 4-channel solvent selection valve on each pump providing versatility for method development. Five to ten minute run times are the norm.
Nexera XR (40-Series) UHPLC System

Nexera XR (40-Series) UHPLC System

Nexera XR is perfect for fast separations using the popular SPP column phases for high efficiency and lower back pressure. This system offers a rugged and forgiving UHPLC workflow. Five to ten minute separations are the norm.
LC/HPLC System

LC-40 HPLC System

Our LC-40 system is the workhorse for everyday HPLC, whether using traditional 5 micron fully porous LC columns or the popular SPP column phases for high efficiency separations with lower back pressures. Ten to 20 minute run times are the norm.
i-Series Plus Integrated HPLC Systems

i-Series Plus Integrated HPLC Systems

Integrated HPLC balancing performance and ease-of-use

Preparative HPLC/SFC Systems

Nexera Prep Preparative HPLC

Nexera Prep HPLC

Rugged and reliable HPLC purification of compounds

Nexera Prep SFC Preparative Supercritical Fluid Chromatography System

Nexera Prep SFC

Rugged and reliable SFC purification of compounds

HPLC Application Specific Systems

i-Series Plus Analyzers

Application Specific Analyzers based on the i-Series Plus

Application specific systems for the analysis of cannabis, hemp, bioethanol, and more
Nexera SFC/SFE System

Nexera UC (SFC/SFE) System

Supercritical fluid extraction and chromatography (SFC/SFE) in a single system
Gel Permeation Chromatography Systems

Gel Permeation Chromatography Systems

Analytical systems optimized for GPC/SEC
Prominence Ion Chromatograph Anion Suppressor Ion Chromatograph

Prominence Ion Chromatograph

New Shimadzu Ion Chromatograph

Analytical HPLC/UHPLC Components

HPLC Solution System Packages

Nexera-i MT Method Transfer System

Nexera-i MT Method Transfer System

Providing easy, seamless method migration in one instrument
Nexera HPLC/UHPLC Method Scouting System

Nexera HPLC/UHPLC Method Scouting System

Automatic column, eluent scouting in analytical methods development

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