Nexera X2 UHPLC System

Nexera X2 UHPLC System

The Shimadzu Nexera X2 ultra high-performance liquid chromatograph (UHPLC) is the most advanced chromatographic system available today. This UHPLC system offers unsurpassed chromatographic efficiency, sensitivity, resolution, stability, and reliability. The Nexera X2 is a truly flexible design that expands to tackle a broad range of UHPLC applications.



Precision Engineered UHPLC Pump

The Nexera X2 solvent delivery unit (LC-30AD) is a world class pump for providing the utmost efficiency and performance using micro-flow rates up to 10 mL/min. Capable of delivering pulse-free solvent with pressures up to 130 MPa for ultra-fast and ultra-high resolution separation.


Solvent Delivery Diagram

Automated Solvent Preparation

Up to 16 mobile phase combinations can be selected for a variety of uses. Automated solvent selection, solvent blending, and/or low pressure gradient elution.


UHPLC/HPLC Switching to Handle Both Analyses

Ability to alternate between UHPLC and HPLC systems using a flow control switching valve.

HPLC Switching Diagram



Multi-Rinse Autosampler Functions

The Nexera X2 series autosamplers have improved its hardware structure to prevent adsorption of those sticky compounds and minimize carryover between injections. The SIL-30AC and SIL-30ACMP offer a multi-rinse mechanism for additional rinsing of the needle and injection port with up to 4 different rinsing solutions.

Multi-Rinse Autosampler Diagram


SIL-30ACMP Autosampler

Maximized Autosampler Throughput

The SIL-30ACMP autosampler maximizes sample throughput allowing six microplates or 1.5 mL vial racks. This autosampler also uses an open access mechanism enhancing work efficiency by allowing users to place new samples into racks that are not involved in sample injection during analysis. And different types of rack plates can be used across the three sample racks.



Ultimate Sensitivity and Resolution

The Nexera X2 photodiode array detector (SPD-M30A) introduces a capillary type cell which gives higher sensitivity and lower dispersion for superior data.

Sensitivity Comparison


LabSolutions Method Scouting for Method Development System

This system streamlines the process for more efficient and accurate method development by automatically switching between up to 96 combinations of unique separation conditions (with up to 6 columns, 8 mobile phases, and 10 gradient settings).

method scouting diagram


CBM web browsing software screen

CBM Web Browsing

Ability to monitor and control you LC system over a network.

solvent pre-heater

Intelligent Heat Balancing Column Temperature Control with Solvent Pre-heater

The intelligent heat balancing mechanism and solvent preheater allows for uniform temperature control throughout the column.

For Research Use Only. Not for use in diagnostic procedures.

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