LCMS-9030 Q-TOF Mass Spectrometer

Research-grade Q-TOF LCMS.  Perform Critical Analysis with Confidence.

Quadrupole Time-of-Flight Liquid Chromatograph Mass Spectrometer - Q-TOF LCMS, Q-TOF Mass Spectrometer

A product of Shimadzu’s engineering DNA, the Q-TOF LCMS-9030 enhances the most important features of Q-TOF instrumentation – mass accuracy, sensitivity and speed – to enable users to effortlessly conduct critical qualitative and quantitative analysis with genuine confidence and ease. Combine with the unmatched solvent delivery of our UHPLC pumps and the rapid cycle times of our sample injectors to achieve unmatched reproducible, high-throughput analysis.

Key benefits include:

Reproducible Results

The LCMS-9030 Q-TOF delivers outstanding mass accuracy over a wide mass range, enabling users to consistently produce accurate identification results. In addition, the LCMS-9030 requires infrequent calibration, making it easy to achieve high mass accuracy over long periods.

High Sensitivity Detection

High efficiency ion guides, quadrupole, and collision cell enable high sensitivity for the detection of trace level compounds. And, due to its robust platform, the LCMS-9030 achieves reproducible quantitative analysis over longer periods of time.

Ultrafast Performance

The LCMS-9030 incorporates the patented ultrafast technologies used in Shimadzu LC-MS/MS platforms to deliver outstanding speed. Innovative TOF architecture enables precise, ultra-fast pulsing of ions into the flight tube and ideal reflection back to the detector. The result is high-speed data acquisition compatible with the high-throughput laboratory.

Compatible with Microflow Analysis

Designed for optimal sensitivity and ease of use, the Micro-ESI 9030 interface brings microflow analysis to the Q-TOF LCMS-9030 using the Nexera Mikros. It detects target components with much higher sensitivity compared to analytical systems, features shorter analysis times and is more durable than nano flowrate compatible LCMS systems.


Core Ion Beam Technologies

Core Ion Beam Technology Component Diagram for Q-TOF LCMS, Q-TOF Mass Spectrometer

The Q-TOF LCMS-9030 builds on proven LC-MS/MS technology and combines it with powerful TOF architecture to create a platform that transforms high mass accuracy workflows. These technologies include:

iRefTof Cutaway Diagram for Q-TOF LCMS


Ion accumulation in the collision cell, synchronized perfectly with short cycles of data acquisition, maximizes sensitivity.


Made with substantial mechanical strength, this grating is able to withstand the high voltages needed for ultrafast ion pulsing.

Funnel MCP

Lossless microchannel plate design maximizes sensitivity.


The temperature-controlled UF-FlightTube requires less frequent calibration, enabling you to run more samples.


Meticulously manufactured plate electrodes are stacked to create a reflectron that delivers a high resolution flight path with highly stable mass accuracy.



LabSolutions LCMS is your single point of control for UHPLC and Q-TOF mass spectrometry data acquisition and analysis, providing researchers with easy, yet flexible workflows. Qualitative and quantitative acquisition modes that fully utilize the capability of the LCMS-9030 are:

  • MS
  • SIM
  • MS/MS
  • MRM
  • MS/MS (DDA)
Three of these modes, MS/MS, MRM, and MS/MS (DDA), allow the user to fully customize settings such as the quadrupole isolation window. 

Featured Application

Monoclonal Antibody Workflows on the Shimadzu Q-TOF LCMS-9030 Using the Protein Metrics Software Suite

Monoclonal Antibody Workflows on the Shimadzu Q-TOF LCMS-9030 Using the Protein Metrics Software Suite

Accurate characterization of monoclonal antibodies is essential to development of biotherapeutics. Thorough understanding of biotherapeutic properties aids in the optimization of bioprocess production, product formulation, and product dosage. In this application note, we use the new Shimadzu Q-TOF LCMS-9030 to characterize the recombinant human IgG1ҝ NIST mAb reference standard as a model of biotherapeutic monoclonal antibodies.

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