Nexera QX Multiplex LC-MS/MS System
High-Throughput UHPLC-MS/MS
Trusted Nexera Performance, Multiplied
Engineering Precision. Unrivaled Results.
Increase LC-MS/MS throughput without adding another mass spectrometer. The Nexera QX Multiplex LC-MS/MS System maximizes mass spectrometer utilization, reduces instrument idle time, and increases laboratory productivity by coordinating multiple UHPLC streams with a single mass spectrometer.
Nexera QX is a high-throughput multiplex LC-MS/MS platform designed to help modern laboratories process more samples, accelerate results, and maximize instrument productivity. By combining multiple UHPLC streams with intelligent scheduling and automated workflow management, it keeps the mass spectrometer operating continuously, increasing throughput and improving return on investment. The system integrates Shimadzu’s Nexera UHPLC hardware, SIL-40 autosamplers, dedicated fluidics, and advanced stream control into a single purpose-built solution. QX Solution software automates critical tasks such as injection timing, stream switching, gradient control, and system flushing, reducing manual intervention and improving workflow efficiency. With dedicated flow paths, automated rinsing, and online sample cleanup, Nexera QX also minimizes carryover and supports reliable quantitative analysis, while Shimadzu’s UFMS-enabled LC-MS/MS technology provides the speed, sensitivity, and robustness required for demanding high-throughput applications.
Features
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Modern laboratories need to process more samples, deliver faster results, and maximize the value of existing analytical instrumentation. Nexera QX combines multiplex UHPLC-MS/MS technology with automated workflow management to increase throughput, reduce analysis time, and improve laboratory efficiency.
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Mass spectrometers create value when they are acquiring data. Nexera QX uses multiple UHPLC streams and intelligent scheduling to maintain continuous MS operation and improve ROI.
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Integrates Nexera UHPLC hardware, SIL-40 autosamplers, intelligent stream control, and dedicated fluidics into a single multiplex platform.
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QX Solution software automates injection timing, stream switching, gradient management, and flushing operations.
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UFMS-enabled Shimadzu LC-MS/MS systems deliver speed, sensitivity, and robustness for high-throughput workflows.
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Dedicated stream pathways, automated rinsing, and online sample cleanup capabilities support reliable quantitative performance.
Videos
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ASMS 2023 Hospitality Suite Tour
Watch this video for an overview of Shimadzu’s key mass spectrometry instruments, platforms, and software on display at the ASMS conference in Houston.
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Nexera QX Multiplex LC-MS/MS Drives Throughput
The Nexera QX Multiplexing module enables high-throughput LCMS analysis. Watch this short clip with Jeremy Smith, Market Manager for Forensics and Clinical at Shimadzu Scientific Instruments, to learn some key product highlights and how this innovative product succeeds in the clinical lab.
News / Events
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ASMS (American Society for Mass Spectrometry) 2026
May 31 - June 4
San Diego Convention Center
San Diego, CA
Suite 5, 6 -
Shimadzu Scientific Instruments Inc. Opens New Laboratory in the San Francisco Bay Area -Accelerating New Product and Business Development for the Pharmaceutical and Life Science Fields
Shimadzu Corporation has positioned North America as a strategic focus area and is committed to expanding its business. Through this South San Francisco Lab, the company aims to position itself as a market leader by delivering unique, next-generation solutions that contribute to the advancement of the industry.
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Shimadzu Announces New LCMS-8065XE Triple Quadrupole Mass Spectrometer
Shimadzu Scientific Instruments announces the LCMS-8065XE, the latest evolution in triple quadrupole mass spectrometry that redefines analytical excellence with world-class sensitivity, efficiency and sustainability.
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Shimadzu Announces New LCMS RX Triple Quadrupole Mass Spectrometry Series
Shimadzu Scientific Instruments announces the new LCMS RX series of triple quadrupole mass spectrometry instruments. These advanced systems are supported by integrated hardware and software technologies to ensure reliable and robust results at lower operating costs, even under the most challenging and dynamic laboratory environments.
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Innovative Technology Developed by Shimadzu and Washington University is Expected to Improve Healthy Life Expectancy
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New Q-TOF LCMS-9050 Delivers Exceptional Mass Accuracy and Fast, Stable Polarity Switching
