CF3-C8030 - Centrifugal Field-Flow Fractionation Unit

Centrifugal Field-Flow Fractionation Unit

A new movement of particle fractionation - Particle Fractionation Measuring Instrument Capable of Accurately Analyzing Nanomaterials
FFF-C8030 Centrifugal Field-Flow Fractionation Unit

Particle Separation Technology Utilizing Centrifugal Force

Centrifugal Field-Flow Fractionation (CF3)

Centrifugal field-flow fractionation (CF3) systems use centrifugal force to fractionate nanomaterials by size, and measure them with various detectors.

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Webinar - Solving Separation Issues in the Analysis of Nanoparticle Drug Delivery Systems using High-Speed Centrifugal Field Flow Fractionation

Principle of Separation in the CF3-C8030 System

1. The sample is injected into the carrier liquid delivered by the liquid delivery pump using the sample injection device, and the sample flows into the rapidly rotating circular channel of the CF3.

Step 1. The sample is injected into the carrier liquid

2. The flow in the channel is stopped and the particles are allowed to settle by centrifugal force.

Step 2. The flow in the channel is stopped and the particles are allowed to settle by centrifugal force

3. The flow is restarted and gradually the rotation speed is reduced to weaken the centrifugal forces acting on the particles. By slowing down the rotation speed, the smaller particles, which experience a smaller centrifugal force and a faster diffusion rate, flow out first. The eluted particles are measured using a detector connected downstream of the separation chamber. By connecting a fraction collector, size-fractionated particles can also be collected.

Step 3. Restart the flow and gradually slow down the rotation speed to weaken the centrifugal force acting on the particles.

Reference Information

The National Institute of Advanced Industrial Science and Technology (AIST)

An example of high-precision size classification is posted on the National Institute of Advanced Industrial Science and Technology's website. They successfully separated particles ranging from 10 nm to 40 µm into smaller particles of the same size.

The world's first: Construction of a centrifugal flow field separator with a centrifugal acceleration exceeding 15,000 G (Source: National Institute of Advanced Industrial Science and Technology).

The CF3-C8030 system is available ONLY in North America

Features

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