Nexera HPLC/UHPLC Autosampler - SIL-40CXS

The beauty of our new autosamplers lies within their ability to maintain ultra-low carryover with fast injection cycles. By placing the needle in the flow path, the entire sample path is constantly being flushed with the mobile phase gradient. Injections are designed to be clean with minimum cycle times, ensuring reliable and rapid analysis. Such autosamplers can be equipped with up to 3 of our new plate changers, allowing users to reach a capacity as high as 16,000+ samples on a single system. Shimadzu’s latest cooled autosamplers can reach the set temperature in 20 minutes, critically important for heat-sensitive samples. Various automated pretreatment functions are now standard on all models, improving throughput and precision by eliminating the need for manual sample preparation. Unique co-injection pretreatment can improve the peak shape of early eluting compounds while avoiding incorrect peak integration. Dual injection mode doubles the throughput and enables 2 complementary analyses to run simultaneously on a single system, saving your precious time and space in the laboratory. LabSolutions software allows results from multiple analyses to be displayed on a single report (using our latest Multi Data Reporting option).


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SIL-40CXS Features

Experience both short cycle times and ultra-low carryover with our fast and efficient SIL-40C XS autosampler, with a UHPLC pressure tolerance of 105 MPa (1050 bar). This model is equipped with a forced air sample cooling mechanism to protect heat-sensitive samples. Its new design utilizes precise, high-speed injection to increase sample throughput and productivity. Sample capacity can be expanded by adding up to three temperature-controlled plate changers. Minimal carryover (due to the needle-in-flowpath design) combined with the precision of a metering pump for sample draw improves your UHPLC experience. The SIL-40C XS autosampler is designed for use with the LC-40D XS UHPLC pumps.


SIL-40CXS Specifications

  • Features a needle in the flow path design to minimize carryover.
  • Standard sample loop (50 µL), an optional sample loop (2000 µL) and a fixed-loop configuration (5 or 20 µL) are available.
  • Total injection method: 0.1 to 50 µL in increments of 0.1 µL from 0.1 to 9.9 µL, and 1 µL from 10-50 µL.
  • Performs sample pretreatment including dilution, reagent addition, co-injection of samples, stacked injection, and overlapped injection.
  • Temperature control from 4 to 45°C (± 2°C accuracy,) with a forced air cooling mechanism to reduce condensation.
  • Industry-leading cycle time of ≤ 7 seconds.
  • Injection volume repeatability: RSD ≤1.0% for 0.5-0.9 µL, RSD ≤0.5% for 1.0-1.9 µL, RSD ≤0.25% for 2.0-4.9 µL, RSD ≤0.15% for injections ≥5.0 µL.
  • Injection volume accuracy of ±1% for 5 μL injections (n=20).
  • Carryover performance: 0.0015% (no needle rinsing) and 0.0003% (with rinse).
  • Equipped with both a static rinse port and an active rinse pump to rinse the outside of the needle before and/or after aspirating sample.
  • A 3-solvent internal rinse option is available to clean the inside of the needle and loop after sample injection to further reduce carryover.
  • A dual injection mechanism can be installed for high throughput operation or complementary analysis.
  • Maximum pressure rating of 105 MPa (1050 bar).

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