Syrfi - Syringes and Filters

Shimadzu’s Syrfi syringe filters and disposable syringes are specifically engineered to provide consistent and reliable results for a wide range of analytes and demanding matrices to deliver exceptional sample preparation performance for a variety of applications.

Count on increased sample throughput, instrument uptime, and column lifetime because Syrfi removes a wide range of particulates from samples prior to HPLC, UHPLC, or LCMS analysis, helping to prevent clogging of the flow path from the autosampler to the column.

Syrfi filters can also be used for sample cleanup before GC and GCMS, UV-Vis, or AA and ICP analysis.

Constructed of ultra clean, low leachable and extractable plastics, Syrfi will not introduce contamination.

Run more samples

Run more cannabis samples using Syrfi, specifically designed to remove a wide range of particulates from samples prior to HPLC or LCMS analysis to prevent clogging of the flow path. Syrfi filters are built with ultra-clean, low leachable and extractable plastics to ensure the reduction of contaminants.

Choosing the right syringe filter is critical when analyzing cannabinoids during potency testing of raw cannabis flower because not all filters are able to remove the complex particles commonly leftover during the extraction process.

A representative chromatogram of 11 cannabinoids at a 10ppm spike of Polypropylene, Nylon, and PTFE filters in raw cannabis flower

A representative chromatogram of 11 cannabinoids at a 10ppm spike in raw cannabis flower.

 

 

 

Cannabis flower is an extremely complex matrix that must be filtered prior to HPLC or LCMS analysis to avoid clogging of the instrument. We evaluated syringe filters used during the sample preparation portion of the Cannabis Analyzer for Potency. The analysis was conducted using the Shimadzu Cannabis Analyzer for Potency High Sensitivity Method (CAP-HS). This analyzer is the most widely used HPLC instrument for determining the potency of cannabinoids found in Cannabis flower. Seven different syringe filter types were tested to determine which filter type was best for filtration of extracted cannabis flower. Three filter types were found to yield acceptable results but the Polypropylene (PP) filter was best.

Choose from these membranes in 2 pore sizes and 2 filter diameters to accommodate small and large volume samples:

Nylon – all-purpose material ideal for dissolution sample analysis, mixed sample matrix of organic and aqueous soluble analytes, and organic solvent extraction cleanup, especially for hemp and cannabis flower samples.

PTFE (Hydrophilic) – recommended for elevated temperatures and most organic solvents, caustic, and acidic solutions. Does not require pre-wetting for high aqueous samples.

PTFE (Hydrophobic) – suitable for the same applications as Hydrophilic PTFE but requires pre-wetting with alcohol before use with aqueous samples. Can be used as a moisture barrier in gaseous venting applications.

Regenerated Cellulose – optimized for samples requiring high recoveries such biological assays, protein-based samples, and gel capsule dissolution testing. Lowest protein binding of any Syrfi membrane.

Polypropylene – hydrophilic, low-binding material ideal for protein and peptide-based samples. Does not require pre-wetting.

PVDF (Hydrophilic) – recommended for aqueous HPLC and UHPLC samples, especially for analysis of pesticides and PPCPs in environmental water samples.

PVDF (Hydrophobic) – suitable for aqueous and organic samples; requires pre-wetting with an alcohol before use with aqueous sample matrices.

Cellulose Acetate – ideal for aqueous solutions and biological samples close to neutral pH. Stable at elevated temperatures for low protein binding and high recovery.

PES (Polyethersulfone) – best choice for ion chromatography (IC) applications, due to certification by ICP for low-level interferences.

Specifications

Syrfi Syringe Filters

 
Filter Material Pore
Size
(um)
Outer
Diameter
(mm)
Max Volume Residual
Volume
Maximum
Operating
Temp
Part Number Pack Size
Nylon 0.2
13
25mL <20uL 100°C 220-97330-40 100 units
0.2
25 100mL <125uL 220-97330-41 100 units
0.45 13 25mL <20uL 220-97330-42 100 units
0.45 25 100mL <125uL 220-97330-43 100 units
PTFE
(HYDROPHILIC)
0.2 13 25mL <20uL 110°C 220-97330-44 100 units
0.2 25 100mL <125mL 220-97330-45 100 units
0.45 13 25mL <20uL 220-97330-46 100 units
0.45 25 100mL <125uL 220-97330-47 100 units
PTFE
(HYDROPHOBIC)
0.2
13 25mL <20uL 110°C 220-97330-48 100 units
0.2 25 100mL <125uL 220-97330-49 100 units
0.45 13 25mL <20uL 220-97330-50 100 units
0.45 25 100mL <125uL 220-97330-51 100 units
REGENERATED
CELLULOSE
0.2 13 25mL <20uL 110°C 220-97330-52 100 units
0.2 25 100mL <125uL 220-97330-53 100 units
0.45 13 25mL <20uL 220-97330-54 100 units
0.45 25 100mL <125uL 220-97330-55 100 units
POLYPROPYLENE 0.2 13 25mL <20uL 110°C 220-97330-56 100 units
0.2 25 100mL <125uL 220-97330-57 100 units
0.45 13 25mL <20uL 220-97330-58 100 units
0.45 25 100mL <125uL 220-97330-59 100 units
PVDF
(HYDROPHILIC)
0.2 13 25mL <20uL 100°C 220-97330-60 100 units
0.2 25 100mL <125uL 220-97330-61 100 units
0.45 13 25mL <20uL 220-97330-62 100 units
0.45 25 100mL <125uL 220-97330-63 100 units
PVDF
(HYDROPHOBIC)
0.2 13 25mL <20uL 100°C 220-97330-64 100 units
0.2 25 100mL <125uL 220-97330-65 100 units
0.45 13 25mL <20uL 220-97330-66 100 units
0.45 25 100mL <125uL 220-97330-67 100 units
CELLULOSE
ACETATE
0.2 13 25mL <20uL 110°C 220-97330-68 100 units
0.2 25 100mL <125uL 220-97330-69 100 units
0.45 13 25mL <20uL 220-97330-70 100 units
0.45 25 100mL <125uL 220-97330-71 100 units
POLYETHERSULFONE 0.2
13
25mL <20uL 100°C 220-97330-72 100 units
0.2 25 100mL <125uL 220-97330-73 100 units
0.45 13 25mL <20uL 220-97330-74 100 units
0.45 25 100mL <125uL 220-97330-75 100 units
 
*Note: All filter membrane materials are HPLC certified. Case material is Polypropylene with female luer lock inlet and male luer slip outlet. All filters are autoclavable to 121oC for 15 minutes. 
 
 
 

Syrfi Disposable Syringes

 
Type Volume Part Number Pack Size
Male Luer Slip 3mL 220-97330-76 100 units
5mL 220-97330-77 100 units
10mL 220-97330-78 100 units
20mL 220-97330-79 100 units
Male Luer lock 3mL 220-97330-80 100 units
5mL 220-97330-81 100 units
10mL 220-97330-82 100 units
20mL 220-97330-83 100 units
 

Chemical Incompatibilities

Filter Type Chemical Incompatibilities
NYLON Acids >1N Halogenated solvents Proteineous samples w/ high non-specific binding affinities            
PTFE
(HYDROPHILIC)
Perchloric acid Limited resistance to methylene chloride Dioxane DMF Formic acid >50%        
PTFE
(HYDROPHOBIC)
Perchloric acid Limited resistance to methylene chloride Dioxane DMF Formic acid >50%        
REGENERATED
CELLULOSE
Sulfuric acid >25% Hydrochloric acid >25% Phosphoric acid >25% Nitric acid >25% DMF Phenols      
POLYPROPYLENE Hexane Toluene Benzene Limited resistance to Dichloromethane and chloroform          
PVDF
(HYDROPHILIC)
DMF DMSO MEK Acetone and caustic solutions >6N          
PVDF
(HYDROPHOBIC)
DMF DMSO MEK Acetone and caustic solutions >6N          
CELLULOSE
ACETATE
Acids >1N NaOH Dichloromethane Chloroform Ketones DMSO THF    
POLYETHERSULFONE Protein based sample in aqueous solutions Concentrated acids Chloromethane Chloroform Hexane Acetone MEK THF DMSO

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