LabSolutions Insight Library Screening:
MRM Spectrum Mode

MRM Spectrum Mode - Rethink your MRM Limits, Rediscover the capabilities of MRM

 

Using ONE concept

ONE Instrument

ONE Instrument

ONE Injection

ONE Injection 

ONE Workflow

ONE Workflow

to achieve two goals at once

 
 

High-Sensitivity Quantitation and High-Confidence Identification in ONE Run

Efficient Icon

Efficient

Streamlined Icon

Streamlined

Reliable Icon

Reliable

Cost-Effective Icon

Cost-Effective

Quantify and Identify using MRM Spectrum Mode

Step 1: Acquire data for all-available MRM (ion fragment) transitions

MRM Spectrum Mode Versus Conventional 2-MRM Method

MRM Spectrum Mode
- Obtains same signal intensity for quantitation as conventional 2-MRM method
- Achieves uncompromised sensitivity with Shimadzu high-speed UFMS

Step 2: Generate the spectrum

Acquired Spectrum

Each fragment ion is optimized for the highest response giving a high-sensitivity mass spectrum.

Step 3: Compare with MRM library spectrum

Acquired Spectrum compared to MRM Library Spectrum

MRM Spectrum Mode
- Achieves much higher confidence in compound identification than product ion scan.
- Reduces the possibility of false positive and false negative reporting to accelerate the data review process.

In Comparison to Existing Screening and Identification Workflows

Increase confidence in identification with all-available MRM transitions. Achieve compromised sensitivity with high-speed UFMS

Resources on MRM Spectrum Mode

Download these resources to learn more on MRM Spectrum Mode and find out how to apply it to accelerate your screening and identification workflow.

Application Notes

Multi-Residue Veterinary Drug Analysis of >200 Compounds using MRM Spectrum Mode by LC-MS/MS

Multi-Residue Veterinary Drug Analysis of >200 Compounds using MRM Spectrum Mode by LC-MS/MS

Fast Quantitative Analysis of Antibiotic Residues in Meat, Eggs and Milk and Identity Confirmation with MRM Spectrum Mode

Fast Quantitative Analysis of Antibiotic Residues in Meat, Eggs and Milk and Identity Confirmation with MRM Spectrum Mode

MRM Spectrum mode and Library Searching for Enhanced Reporting Confidence in Forensic Toxicology

MRM Spectrum mode and Library Searching for Enhanced Reporting Confidence in Forensic Toxicology

Applying MRM Spectrum mode and Library Searching for Enhanced Reporting Confidence in Pesticide Residue Analysis

Applying MRM Spectrum mode and Library Searching for Enhanced Reporting Confidence in Pesticide Residue Analysis

Peer-Reviewed Journal Publications

Dried Blood Spots

Fully Automated Forensic Routine Dried Blood Spot Screening for Workplace Testing
Gaugler, S.; Al-Mazroua, M. K. et al., Journal of Analytical Toxicology,
Published: 01 October 2018.

Fully Automated Drug Screening of Dried Blood Spots using Online LC-MS/MS Analysis
Gaugler, S.; Rykl, J. et al., Journal of Applied Bioanalysis, 2018, 4(1), 7-15.

Infographic

MRM Spectrum Mode Infographic

Download 

LabSolutions Insight Multi-Analyte Software for Mass Spectrometry

For Research Use Only. Not for use in diagnostic procedures.

Top of This Page