High-Resolution and High-Speed Simultaneous Analysis of Preservatives in Cosmetics Using SPP Column

This article introduces a method for the analysis of 24 types of cosmetic preservatives, either specified in the cosmetics standards established by the Japanese Ministry of Health, Labour and Welfare or regulated by the European Commission, using ultra-high performance liquid chromatography (UHPLC). Analyses were performed using the Nexera™ series UHPLC system equipped with a Shim- pack Velox™ C18 SPP (superficially porous particles, core-shell) column, which enabled both high resolution and reduced assay time.