Analysis of Per- and Polyfluoroalkyl Substances (PFAS) - Applications : Shimadzu Scientific Instruments

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Featured Applications

Featured Applications

Access below our featured applications and other documents that will help you to streamline your PFAS analysis workflows.

EPA Method 1633: Method Detection Limits of Per-and Polyfluoroalkyl Substances (PFAS) in Aqueous Matrices using the Triple Quad LCMS-8060NX

Regulations for controlling the occurrence of PFAS in different environmental samples are developing fast. With the final approval of EPA method 1633, environmental laboratories have now a new standardized method to respond to the demand for PFAS analysis in complex environmental samples, such as wastewater, solid, biosolids, and tissue. Discover how to achieve reproducible results and quantification 10x lower than the EPA’s Limit of Quantitation for the analysis of PFAS wastewater according to EPA Method 1633.

EPA 537.1 for PFAS analysis with the Shimadzu LCMS-8050: Demonstration of instrument and method performance.

Here we provide a framework for laboratories to evaluate the performance of each the individual steps performed in the laboratory for the analysis of PFAS by EPA method 537.1, including extraction and instrumental analysis. Discover how to implement an enhanced workflow that consistently achieves up to four times better detection limits for all targeted classes PFAS included in EPA method 537.1, even with a small injection volume of 2 µL using the Shimadzu’s LCMS-8050.

EPA 533 for PFAS analysis with the Shimadzu’s LCMS-8050: Demonstration of instrument and method performance.

The enhanced analytical workflow (including sample preparation) from this work provides greater efficiency, achieving over 50% faster run times and reduced injection volumes down to 2 µL, for supporting PFAS regulation in drinking water. This leads to quicker analyses, less solvent use, and improved lab productivity. Learn more about the performance of the Shimadzu LCMS-8050 as part of a complete workflow for analyzing the target PFAS specified in EPA method 533.