an effective analysis method for molecules having a high
molecular weight such as proteins and peptides. However,
this method can also be used for low-molecular
compounds as a rapid, simple analysis method. In particular,
since the analysis is hardly affected by salts that may be
contained in samples, target components in the product
can be analyzed directly without any pretreatment such as
purification. For example, commercially available oral care
products contain bactericidal components (povidoneiodine,
chlorhexidine gluconate, etc.), and such lowmolecular
antiseptic components can be directly detected
from the products.
This article introduces examples of detecting antiseptic
components from commercially available oral care
products using a benchtop MALDI-TOF mass spectrometer.